406676-35-5 Usage
Uses
Used in Organic Synthesis:
3,5-dichloro-2-fluoro-6-iodopyridine is utilized as a building block in organic synthesis, allowing for the creation of more complex molecules with tailored properties and functions. Its versatile structure makes it a valuable component in the development of new organic compounds.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 3,5-dichloro-2-fluoro-6-iodopyridine is employed as a key intermediate for the synthesis of pharmaceuticals. Its unique structure and halogen substituents can be leveraged to design and develop novel drugs with specific therapeutic targets and improved efficacy.
Used in Pharmaceutical Development:
3,5-dichloro-2-fluoro-6-iodopyridine may possess biological activity, making it a candidate for the development of new pharmaceuticals. Its potential use in drug discovery can lead to the creation of innovative treatments for various diseases and conditions.
Used in Agrochemicals:
3,5-dichloro-2-fluoro-6-iodopyridine is also of interest in the development of agrochemicals, where its unique properties can be harnessed to create new products for agricultural applications. This can include the development of pesticides, herbicides, or other chemicals to improve crop yield and protect against pests.
The specific properties and uses of 3,5-dichloro-2-fluoro-6-iodopyridine can vary depending on its application and the other chemicals it interacts with, highlighting its potential for diverse and innovative uses across multiple industries.
Check Digit Verification of cas no
The CAS Registry Mumber 406676-35-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,0,6,6,7 and 6 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 406676-35:
(8*4)+(7*0)+(6*6)+(5*6)+(4*7)+(3*6)+(2*3)+(1*5)=155
155 % 10 = 5
So 406676-35-5 is a valid CAS Registry Number.
406676-35-5Relevant academic research and scientific papers
Regiochemical flexibility: The optional functionalization of 2,3,5-trihalopyridines at the 4- or 6-position
Bobbio, Carla,Schlosser, Manfred
, p. 4533 - 4536 (2007/10/03)
A deprotonation study was performed using 2,3,5-trichloropyridine, 3,5-dichloro-2-fluoropyridine and 5-chloro-2,3-difluoropyridine as the substrates. Upon reaction with lithium diisopropylamide (LDA), deprotonation occurred exclusively at the 4-position. Subsequent carboxylation and iodination led to the acids 1 and 4-iodopyridines 2. The exposure of the latter compounds to lithium 2,2,6,6-tetramethylpiperidide (LITMP) caused deprotonation and immediately ensuing iodine migration. The intermediates were trapped with dry ice to afford the carboxylic acids 3. Upon neutralization, the 6-iodopyridines 4 were obtained. These compounds readily exchanged the heavy halogen for metal when treated with isopropylmagnesium chloride. In this way, functional groups could be selectively introduced in the 6-position. Employing carbon dioxide routinely as the model electrophile, trihalopyridinecarboxylic acids were formed which, all unknown so far, should provide valuable new building blocks for pharmaceutical research. Moreover, the selective nucleophilic displacement of the halogen at the 2-position could give rise to an immense variety of new structures.
