40677-44-9

Usage

Uses

Used in Pharmaceutical Industry:
2-AMINO-4,6-DICHLORO-5-METHYLPHENOL is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its role in drug production is crucial due to its ability to be incorporated into the molecular structures of different medicinal compounds, contributing to their therapeutic effects.
Used in Dye Industry:
In the dye industry, 2-AMINO-4,6-DICHLORO-5-METHYLPHENOL is used as an intermediate in the production of dyes. Its chemical properties allow it to be a key component in the creation of colorants used in various applications, including textiles and other industrial processes.
Used in Cosmetic and Personal Care Products:
2-AMINO-4,6-DICHLORO-5-METHYLPHENOL is used as an antimicrobial ingredient in some cosmetic and personal care products. Its inclusion helps to prevent the growth of harmful microorganisms, ensuring the safety and efficacy of these products for consumer use.

InChI:InChI=1/C7H7Cl2NO/c1-3-4(8)2-5(10)7(11)6(3)9/h2,11H,10H2,1H3

Upstream product

• 53524-27-9 2-amino-4-chloro-5-methylphenol 
• 17788-00-0 2,4-dichloro-3-methylphenol 
• 39549-27-4 2,4-Dichloro-3-methyl-6-nitro-phenol 

Downstream Products

• 31037-84-0 2-(2,4-di-tert-pentyl-phenoxy)-butyric acid-(3,5-dichloro-2-hydroxy-4-methyl-anilide) 
• 199293-12-4 5,7-dichloro-2-mercapto-6-methylbenzoxazole 
• 72616-70-7 C₁₄H₁₀N₂O₄Cl₂ 
• 921198-87-0 9-fluorenylmethyl 3,5-dichloro-2-hydroxy-4-methylphenylcarbamate 
• 1446428-11-0 1,3-dichloro-4-methoxy-2-methyl-5-(trifluoromethyl)benzene 
• 94109-73-6 {4-[2-(2,4-di-tert-pentyl-phenoxy)-butyrylamino]-phenoxy}-acetic acid-(3,5-dichloro-2-hydroxy-4-methyl-anilide) 
• 102881-35-6 (4-amino-phenoxy)-acetic acid-(3,5-dichloro-2-hydroxy-4-methyl-anilide) 

Relevant academic research and scientific papers

Method for producing 5-substituted 2-amidophenol

E>>[PROBLEM TO BE SOLVED]: To provide a method for producing color coupler for a low-priced silver halide photography.[SOLUTION]: When the color coupler for the silver halide photography is manufactured from o-aminophenols obtained by catalytic reduction of o-nitrophenols and the acid halides, the solvent of alcohols can be used by contraries, and it is possible to execute it from the catalytic reduction and the amidification condensation reaction to the refinement in the single solvent, and produce low-priced cyan coupler without remaining the undesirable by-product on the photograph performances as fog and the desensitization, etc in the cyan coupler.

Benzoxazole derivatives as novel 5-HT3 receptor partial agonists in the gut

A series of benzoxazoles with a nitrogen-containing heterocyclic substituent at the 2-position was prepared and evaluated for 5-HT3 partial agonist activity on isolated guinea pig ileum. The nature of the substituent at the 5-position of the benzoxazole ring affected the potency for the 5-HTs receptor, and the 5-chloro derivatives showed increased potency and lowered intrinsic activity. 5-Chloro-7-methyl-2-(4-methyl-1- homopiperazinyl)benzoxazole (6v) exhibited a high binding affinity in the same range as that of the 5-HT3 antagonist granisetron, and its intrinsic activity was 12% of that of 5-HT. Compound 6v inhibited 5-HT-evoked diarrhea but did not prolong the transition time of glass beads in the normal distal colon even at a dose of 100 times the ED50 for diarrhea inhibition in mice. Compounds of this type are expected to be effective for the treatment of irritable bowel syndrome without the side effect of constipation.