53524-27-9

Basic information

• Product Name: 2-AMINO-4-CHLORO-5-METHYL PHENOL
• Synonyms: 2-AMINO-4-CHLORO-5-METHYL PHENOL;3-Methyl-4-chloro-6-aminophenol;Einecs 258-606-8;Phenol, 2-amino-4-chloro-5-methyl-
• CAS NO: 53524-27-9
• Molecular Formula: C₇H₈ClNO
• Molecular Weight: 157.59752
• EINECS: 258-606-8
• Mol File: 53524-27-9.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 281.5 °C at 760 mmHg
• Flash Point: 124 °C
• Appearance: /
• Density: 1.331 g/cm³
• Vapor Pressure: 0.00209mmHg at 25°C
• Refractive Index: 1.629
• CAS DataBase Reference: 2-AMINO-4-CHLORO-5-METHYL PHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-4-CHLORO-5-METHYL PHENOL(53524-27-9)
• EPA Substance Registry System: 2-AMINO-4-CHLORO-5-METHYL PHENOL(53524-27-9)

Safety Data

• Hazardous Substances Data: 53524-27-9(Hazardous Substances Data)

Usage

General Description

2-Amino-4-chloro-5-methyl phenol is a chemical compound with the molecular formula C7H8ClNO. It is a derivative of phenol and is commonly used as a hair dye ingredient. The compound is a white to light brown crystalline powder that is slightly soluble in water and ethanol. It is also known to have antibacterial and antifungal properties, and is used in the synthesis of various pharmaceuticals. However, it is important to handle this compound with care and ensure appropriate safety measures are in place when working with it due to its potential adverse health effects.

InChI:InChI=1/C7H8ClNO/c1-4-2-7(10)6(9)3-5(4)8/h2-3,10H,9H2,1H3

Upstream product

• 496847-14-4 n-propanol water 
• 7147-89-9 4-chloro-5-methyl-2-nitrophenol 
• 7439-89-6 iron 
• 59-50-7 4-Chloro-3-methylphenol 

Downstream Products

• 153506-14-0 acetic acid-(5-chloro-2-hydroxy-4-methyl-anilide) 
• 118794-10-8 5-chloro-6-methylbenzo[d]oxazol-2(3H)-one 
• 118794-30-2 5-Chloro-3-[(4-methoxy-phenylamino)-methyl]-6-methyl-3H-benzooxazole-2-thione 
• 118794-34-6 *H₂O 
• 118794-27-7 4-[(5-Chloro-6-methyl-2-oxo-benzooxazol-3-ylmethyl)-amino]-benzoic acid 
• 118794-26-6 4-[(5-Chloro-6-methyl-2-thioxo-benzooxazol-3-ylmethyl)-amino]-benzoic acid 
• 118794-29-9 *0.5H₂O 
• 118794-28-8 *H₂O 
• 118794-36-8 *0.5H₂O 
• 118794-35-7 5-Chloro-6-methyl-3-[(4-morpholin-4-yl-phenylamino)-methyl]-3H-benzooxazole-2-thione 
• 118794-37-9 *0.5H₂O 
• 105296-08-0 2-acetylamino-5-methyl-[1,4]benzoquinone-4-(4-dimethylamino-phenylimine) 
• 1421257-28-4 C₂₁H₂₈ClN₃O₃ 
• 51207-42-2 toluene-4-sulfonic acid-(2,4-dichloro-5-methyl-phenyl ester) 

Relevant articles and documents

ANTIBIOTIC COMPOUNDS

The present invention relates to antibiotic compounds of formula (I), to compositions containing these compounds and to methods of treating bacterial diseases and infections using the compounds. The compounds find application in the treatment of infection with, and diseases caused by, Gram-positive and/or Gram-negative bacteria, and in particular in the treatment of infection with, and diseases caused by, Neisseria gonorrhoeae.

Novel benzoxazolone compound

PROBLEM TO BE SOLVED: To provide a therapeutic agent for diseases such as neuropathic pain, nociceptive pain, inflammatory pain, small diameter fiber neuropathy, erythromelalgia, paroxysmal extreme pain disorder, dysuria or multiple sclerosis. SOLUTION: There is provided a benzoxazolone compound represented by the formula (1) or a pharmaceutically acceptable salt. (1), where R1 and R2 are each independently H or C1-6 alkyl, where the alkyl may be substituted by hydroxy, C1-4 alkylsulfonyl, aminocarbonyl or 4 to 7-membered heterocycloalkyl, or the like, L is C1-6 alkylene, R3 is C1-6 alkyl, C3-7 cycloalkyl, where the cycloalkyl may be substituted by halogen or hydroxy or the like, C6-10 aryl, where the aryl may be substituted by halogen, C1-4 alkyl or C1-4 haloalkyl or the like, R4 is H, halogen or C1-4 alkyl. SELECTED DRAWING: None COPYRIGHT: (C)2017,JPOandINPIT

ANTI-TRICHOPHYTIC ADHESIVE PATCH

According to the present invention, a patch for nail and/or skin having antifungal activity against dermatophytes, and having higher nail permeability can be provided. The patch for nail and/or skin for prevention or treatment of dermatophytosis comprises in a pressure sensitive adhesive layer a compound represented by the formula: wherein R1 represents a hydrogen atom, C1-6 alkyl, or trifluoromethyl; R2 represents a hydrogen atom, C1-6 alkyl, halogen, -COO(C1-6 alkyl), or (CH2)1-3COOR (R represents a hydrogen atom or C1-6 alkyl); R3 represents a hydrogen atom, C1-6 alkyl, amino, trifluoromethyl, or OR (R represents a hydrogen atom or C1-6 alkyl); R4 represents a hydroxyl group; R5 represents a hydrogen atom, C1-6 alkyl, a hydroxyl group, or halogen; R6 represents a hydrogen atom, C1-6 alkyl, trifluoromethyl, halogen, amino, -NRaRb, nitro, hydroxy-C1-6 alkyl, -CONRaRb, -COO(C1-6 alkyl), -COOH, -(CH2)1-3COOR, or ORa (R represents a hydrogen atom or C1-6 alkyl, Ra and Rb may be the same or different from each other, and each represent a hydrogen atom, C1-6 alkyl, or C1-6 acyl); R7 represents a hydrogen atom, C1-6 alkyl, -OR (R represents a hydrogen atom or C1-6 alkyl), or halogen; and R8 represents a hydrogen atom, C1-6 alkyl, a hydroxyl group, amino, or nitro, or a salt thereof.