406933-21-9

Basic information

• Product Name: 2-Cyano-3-trifluoromethylpyridine
• Synonyms: 2-Cyano-3-trifluoromethylpyridine;3-Trifluoromethylpicolinonitrile;3-(Trifluoromethyl)-2-picolinonitrile, 2-Cyano-3-(trifluoromethyl)pyridine;3-Trifluoromethyl-2-pyridinecarbonitrile 2-Cyano-3-trifluoromethylpyridine
• CAS NO: 406933-21-9
• Molecular Formula: C₇H₃F₃N₂
• Molecular Weight: 172.11
• Mol File: 406933-21-9.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 241℃
• Flash Point: 99℃
• Appearance: /
• Density: 1.37
• Vapor Pressure: 0.038mmHg at 25°C
• Refractive Index: 1.457
• Storage Temp.: Room temperature.
• PKA: -2.75±0.10(Predicted)
• CAS DataBase Reference: 2-Cyano-3-trifluoromethylpyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyano-3-trifluoromethylpyridine(406933-21-9)
• EPA Substance Registry System: 2-Cyano-3-trifluoromethylpyridine(406933-21-9)

Safety Data

• Hazardous Substances Data: 406933-21-9(Hazardous Substances Data)

Usage

General Description

2-Cyano-3-trifluoromethylpyridine is a chemical compound with the molecular formula C7H3F3N2. It is a pyridine derivative with a cyano group and a trifluoromethyl group attached to the third and fourth positions of the pyridine ring, respectively. 2-Cyano-3-trifluoromethylpyridine is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals. It is also utilized in organic synthesis as a reagent in various chemical reactions. 2-Cyano-3-trifluoromethylpyridine is a valuable compound in the field of medicinal chemistry and has found applications in the development of new drugs and biologically active compounds.

InChI:InChI=1/C7H3F3N2/c8-7(9,10)5-2-1-3-12-6(5)4-11/h1-3H

Upstream product

• 65753-47-1 2-chloro-3-trifluoromethyl-pyridine 
• 557-21-1 zinc(II) cyanide 
• 557-21-1 dicyanozinc 
• 3796-23-4 3-(trifluoromethyl)pyridine 
• 7677-24-9 trimethylsilyl cyanide 
• 22253-72-1 3-(trifluoromethyl)pyridine-N-oxide 

Downstream Products

• 749257-78-1 1-[3-(trifluoromethyl)pyridin-2-yl]ethane-1-one 
• 573762-57-9 2-cyano-3-(trifluoromethyl)-5-nitropyridine 
• 573762-62-6 5-amino-3-(trifluoromethyl)pyridine-2-carbonitrile 
• 951753-87-0 5-isothiocyanato-3-(trifluoromethyl)pyridine-2-carbonitrile 
• 832692-66-7 7-[3-(trifluoromethyl)pyridin-2-yl]-N-[5-(trifluoromethyl)-pyridin-2-yl]-1,8-naphthyridin-4-amine 
• 886371-24-0 1-[3-(trifluoromethyl)pyridin-2-yl]methanamine 
• 1396734-59-0 C₁₂H₁₅F₃N₂O₂ 

Relevant articles and documents

USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS VIII

The present invention relates to the use of strobilurin type compounds of formula I and the N-oxides and the salts thereof for combating phytopathogenic fungi containing an amino acid substitution F129L in the mitochondrial cytochrome b protein (also referred to as F129L mutation in the mitochondrial cytochrome b gene) conferring resistance to Qo inhibitors, and to methods for combating such fungi. The invention also relates to novel compounds, processes for preparing these compounds, to compositions comprising at least one such compound, and to seeds coated with at least one such compound.

ANDROGEN RECEPTOR MODULATOR FOR TREATMENT OF PROSTATE CANCER AND ANDROGEN RECEPTOR-ASSOCIATED DISEASES

PROBLEM TO BE SOLVED: To provide a series of compounds that modulate the function of the nuclear hormone receptors, especially the androgen receptor. SOLUTION: The present invention relates to hydantoin compounds, methods of using such compounds in the treatment of androgen receptor-associated conditions, such as age-related diseases, for example, prostate cancer, and to pharmaceutical compositions containing such compounds. In an embodiment, a pharmaceutical composition includes a therapeutically effective amount of a compound according to the formula II, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, diluent, or adjuvant. The present invention provides a series of compounds that modulate the function of the nuclear hormone receptors, especially the androgen receptor. These compounds can cause disappearance of prostate cancer cells and tumors. COPYRIGHT: (C)2016,JPOandINPIT

Substituted (7-pyridyl-4-phenylamino-quinazolin-2-yl)-methanol analogues

Substituted (7-pyridyl-4-phenylamino-quinazolin-2-yl)-methanol analogues are provided. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions assoc