406938-50-9Relevant academic research and scientific papers
Total synthesis of the cyclic peptide Argyrin B
Ley, Steven V.,Priour, Alain
, p. 3995 - 4004 (2007/10/03)
The details of the total synthesis of Argyrin B, a natural product with immunosuppressive properties, are reported below. The two most unusual amino acid residues of this cyclic peptide are 4-methoxytryptophan and dehydroalanine, which were obtained by mo
Total synthesis of the cyclic heptapeptide Argyrin B: A new potent inhibitor of T-cell independent antibody formation
Ley, Steven V.,Prieur, Alain,Heusser, Christoph
, p. 711 - 714 (2007/10/03)
(equation presented) Argyrin B (1) The total synthesis of Argyrin B (1) is presented using a synthetic plan that is convergent and flexible and conserves the stereogenic centers. The unusual amino acid 4-methoxy tryptophan (6) was obtained via an enzymati
