406938-58-7

Upstream product

• 1026935-30-7 D-Abu-(Ph)Sec-Sar-OEt 
• 4837-90-5 4-methoxy-1H-indole 
• 52335-75-8 (4-methoxy-1H-indol-3-ylmethyl)dimethylamine 
• 3744-87-4 Boc-(R)-Ala 
• 112495-90-6 (R)-2-(1-((tert-butoxycarbonyl)amino)ethyl)thiazole-4-carboxylic acid 
• 111946-75-9 1'-(R)-2-(1-tert-butoxycarbonylaminoethyl)thiazole-4-carboxylic acid ethyl ester 
• 78981-25-6 N-(tert-butoxycarbonyl)-D-alanine amide 
• 268553-44-2 tert-butyl (R)-(1-amino-1-thioxopropan-2-yl)carbamate 
• 406938-53-2 4-methoxy-L-tryptophan 
• 1026562-22-0 (4-OMe)Trp-Gly-OMe 
• 406938-56-5 Boc-(Ph)Sec-Sar-OEt 
• 406938-52-1 3-(4-methoxy-1H-indol-3-yl)-2-phenylacetylaminopropionic acid 
• 406938-51-0 (S)-2-benzyloxycarbonylamino-3-(4-methoxy-1H-indol-3-yl)propionic acid 
• 1666-13-3 diphenyl diselenide 

Downstream Products

• 406938-59-8 Cyclo[D-AlaThz-L-Trp-L-(4-OMe)Trp-Gly-D-Aby-L-(Ph)Sec-Sar] 

Relevant academic research and scientific papers

Total synthesis of the cyclic heptapeptide Argyrin B: A new potent inhibitor of T-cell independent antibody formation

(equation presented) Argyrin B (1) The total synthesis of Argyrin B (1) is presented using a synthetic plan that is convergent and flexible and conserves the stereogenic centers. The unusual amino acid 4-methoxy tryptophan (6) was obtained via an enzymati

Total synthesis of the cyclic peptide Argyrin B

The details of the total synthesis of Argyrin B, a natural product with immunosuppressive properties, are reported below. The two most unusual amino acid residues of this cyclic peptide are 4-methoxytryptophan and dehydroalanine, which were obtained by mo