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Kainic acid dimethyl ester, also known as KAIN, is a synthetic analog of kainic acid, a neuroexcitatory amino acid found in seaweed. It is used as a research tool in neuroscience to study the effects of glutamate, the primary excitatory neurotransmitter in the central nervous system. KAIN acts as a potent agonist at certain types of glutamate receptors, particularly the kainate receptors, which are involved in synaptic transmission and plasticity. By binding to these receptors, KAIN can induce neuronal depolarization and increase the release of neurotransmitters, leading to excitotoxicity in high concentrations. This property makes it valuable for investigating the role of glutamate in various neurological processes, including learning, memory, and neurodegenerative diseases. However, due to its potential neurotoxic effects, KAIN is not used clinically and is strictly confined to laboratory settings.

4071-37-8

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4071-37-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 4071-37-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,0,7 and 1 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 4071-37:
(6*4)+(5*0)+(4*7)+(3*1)+(2*3)+(1*7)=68
68 % 10 = 8
So 4071-37-8 is a valid CAS Registry Number.

4071-37-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name Kainic acid dimethyl ester

1.2 Other means of identification

Product number -
Other names (+/-)-

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

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More Details:4071-37-8 SDS

4071-37-8Downstream Products

4071-37-8Relevant academic research and scientific papers

Synthesis of kainoids via a highly stereoselective hydroformylation of kainic acid

Rodriquez, Manuela,Bassarello, Carla,Bifulco, Giuseppe,Gomez-Paloma, Luigi,Mann, André,Marchetti, Mauro,Schoenfelder, Angèle,Taddei, Maurizio

, p. 1581 - 1585 (2007/10/03)

An efficient preparation of a series of secondary amines, structurally related to the kainic acid scaffold, is described. Naturally occurring (-)-α-kainic acid was hydroformylated with complete terminal selectivity and high stereoselectivity. The stereoch

Pelladium(II)-Catalyzed Olefin-Coupling Reactions of Kainic Acid: Effects of Substitution on the Isopropenyl Group on Receptor Binding

Convay, Gregory A.,Park, Joon Sup,Maggiora, Linda,Mertes, Mathias P.,Galton, Noemi,Michaelis, Elias K.

, p. 52 - 56 (2007/10/02)

Two palladium-catalyzed carbon-carbon bond forming reactions were found to be useful for the modification of a protected amino acid derivative containing a sterically hindered isopropenyl group.Arylation of the terminal methylene group of the dimethyl est

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