40731-16-6 Usage
Uses
Used in Pharmaceutical Industry:
5-CHLORO-3-METHYL-1H-INDOLE-2-CARBALDEHYDE is used as an intermediate or building block in organic synthesis for the production of pharmaceuticals. Its unique chemical properties and reactivity make it a valuable component in the development of various medications.
Used in Agrochemical Industry:
5-CHLORO-3-METHYL-1H-INDOLE-2-CARBALDEHYDE is also used as an intermediate in the synthesis of agrochemicals. Its specific chemical structure allows it to be incorporated into compounds that can be used in the development of pesticides and other agricultural products.
Check Digit Verification of cas no
The CAS Registry Mumber 40731-16-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,7,3 and 1 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 40731-16:
(7*4)+(6*0)+(5*7)+(4*3)+(3*1)+(2*1)+(1*6)=86
86 % 10 = 6
So 40731-16-6 is a valid CAS Registry Number.
InChI:InChI=1/C10H8ClNO/c1-6-8-4-7(11)2-3-9(8)12-10(6)5-13/h2-5,12H,1H3
40731-16-6Relevant academic research and scientific papers
En Route to 2-(Cyclobuten-1-yl)-3-(trifluoromethyl)-1H-indole
Gazvoda, Martin,Krivec, Marko,?asar, Zdenko,Ko?mrlj, Janez
, p. 2486 - 2493 (2018/02/23)
A six-step synthetic route from 4-chloro-2-methylaniline to 5-chloro-2-(cyclobut-1-en-1-yl)-3-(trifluoromethyl)-1H-indole (1) has been reported. Compound 1a is a key impurity of reverse transcriptase inhibitor efavirenz, an important anti-HIV/AIDS drug. Synthetic challenges, dead ends, and detours are discussed.
Synthesis & Reaction of Indole-1,2-dicarboxaldehydes with Hydrazine & Hydroxylamine
Hiremath, Shivayogi P.,Thakar, Shreeram B.,Purohit, Muralidhar G.
, p. 770 - 774 (2007/10/02)
Indole-1,2-dicarboxaldehydes (2a-g) have been prepared by formylation of 3-methylindole-2-carboxaldehydes (1a-g) with DMF-POCl3 at 140 deg C. 2a-e react with N2H4.H2O to give hydrazones (3a-e and 3g) of 1-formylindole-2-carboxaldehydes instead of the tria
