40732-50-1Relevant academic research and scientific papers
ADENOSINE CYCLIC 3',5'-PHOSPHORAMIDATE AND N,N-DIMETHYLPHOSPHORAMIDATE: SYNTHESIS VIA SYMMETRICAL AND MIXED ANHYDRIDES AND HYDROLYSIS
Tomasz, Jenoe,Bottka, Sandor,Ludwig, Janos,Pelczer, Istvan
, p. 597 - 600 (2007/10/02)
The title compounds were synthesized by converting cyclic AMP with a sulfonyl chloride to the symmetrical anhydride or with diphenyl phosphorochloridate to the mixed anhydride, then aminolyzing the anhydrides without isolation.The synthesis preferentially gave SP-amides.Characteristic differences were observed in the behavior of the unsubstituted amide and the dimethylamide under hydrolysis conditions.
