40740-57-6 Usage
Uses
Used in Organic Synthesis:
5-Fluoro-benzo[b]thiophene-3-carboxylic acid is used as an intermediate in organic synthesis for the preparation of various compounds. Its carboxylic acid functional group allows for further chemical reactions and modifications, making it a versatile building block in the synthesis of complex organic molecules.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 5-Fluoro-benzo[b]thiophene-3-carboxylic acid is used as an intermediate in the preparation of pharmaceuticals. Its unique structure and properties can be exploited to design and develop new drugs with potential therapeutic applications.
Used in Agrochemicals:
5-Fluoro-benzo[b]thiophene-3-carboxylic acid is also used as an intermediate in the preparation of agrochemicals. Its chemical properties can be utilized to create new compounds with pesticidal or herbicidal activity, contributing to the development of more effective and environmentally friendly agricultural products.
Used in Research and Development:
Due to its unique structure and properties, 5-Fluoro-benzo[b]thiophene-3-carboxylic acid is an interesting target for research and development in the field of organic chemistry. Scientists and researchers can explore its potential applications and investigate its chemical behavior to gain insights into the design and synthesis of new compounds with various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 40740-57-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,7,4 and 0 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 40740-57:
(7*4)+(6*0)+(5*7)+(4*4)+(3*0)+(2*5)+(1*7)=96
96 % 10 = 6
So 40740-57-6 is a valid CAS Registry Number.
40740-57-6Relevant academic research and scientific papers
Synthesis and biological activity of various derivatives of a novel class of potent, selective, and orally active prostaglandin D2 receptor antagonists. 2. 6,6-dimethylbicyclo[3.1.1]heptane derivatives
Mitsumori, Susumu,Tsuri, Tatsuo,Honma, Tsunetoshi,Hiramatsu, Yoshiharu,Okada, Toshihiko,Hashizume, Hiroshi,Inagaki, Masanao,Arimura, Akinori,Yasui, Kiyoshi,Asanuma, Fujio,Kishino, Junji,Ohtani, Mitsuaki
, p. 2446 - 2455 (2007/10/03)
In an earlier paper, we reported that novel prostaglandin D2 (PGD2) receptor antagonists having the bicyclo[2.2.1]heptane ring system as a prostaglandin skeleton were a potent new class of antiallergic agents and suppressed various allergic inflammatory responses such as those observed in conjunctivitis and asthma models. In the present study, we synthesized PGD2 receptor antagonists having the 6,6-dimethylbicyclo [3.1.1]heptane ring system. These derivatives have the amide moiety, in contrast to those with the bicyclo[2.2.1]heptane ring system, which have the sulfonamide group. The derivatives having the 6,6-dimethylbicyclo[3.1.1]heptane ring also exhibited strong activity in PGD2 receptor binding and cAMP formation assays. In in vivo assays such as allergic rhinitis, conjunctivitis, and asthma models, these series of derivatives showed excellent pharmacological profiles. In particular, compound 45 also effectively suppressed eosinophil infiltration in allergic rhinitis and asthma models. This compound (45, S-5751) is now being developed as a promising alternative antiallergic drug candidate.
