40748-46-7Relevant academic research and scientific papers
SYNTHESIS OF 2-(4-PIPERIDYLMETHYL)INDOLES FOR THE SYNTHESIS OF STRYCHNOS ALKALOIDS
Bonjoch, Josep,Quirante, Josefina,Linares, Ana,Bosch, Joan
, p. 2883 - 2890 (2007/10/02)
The synthesis of 2-indole (6) by three alternative procedures is reported, the condensation of the organodilithium derivative of N-trimethylsilyl-o-toluidine with ethyl cis-1-benzyl-3-ethyl-4-piperidineacetate (1
Mercuric acetate cyclization of 4-(arylmethyl)piperidines: Synthesis of indolo[2,3-g]morphans (tetracyclic ring system of strychnos indole alkaloids) and 7,8-benzomorphans
Bosch,Bonjoch,Diez,et al.
, p. 1753 - 1762 (2007/10/02)
A new synthetic route to indolo[2,3-g]morphans and 7,8-benzomorphans is reported. The key step in these syntheses is the mercuric acetate oxidation of appropriate 2-(4-piperidyl-methyl)indoles or 4-benzylpiperidines, respectively. An alternative synthetic
