4075-41-6

Basic information

• Product Name: (14E,24E)-8-[(diethylamino)methyl]-5,6,9,17,19-pentahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-1,2-dihydro-2,7-(epoxypentadeca[1,11,13]trienoimino)naphtho[2,1-b]furan-21-yl acetate
• Synonyms: 2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-1,11(2H)-dione, 5,6,9,17,19,21-hexahydroxy-2,4,12,16,18,20,22-heptamethyl-23-methoxy-8-(diethylaminomethyl)-, 21-acetate
• CAS NO: 4075-41-6
• Molecular Formula: C₄₂H₅₈N₂O₁₂
• Molecular Weight: 782.9161
• Mol File: 4075-41-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 877.6°C at 760 mmHg
• Flash Point: 484.5°C
• Density: 1.3g/cm³
• Vapor Pressure: 5.92E-33mmHg at 25°C
• Refractive Index: 1.618
• CAS DataBase Reference: (14E,24E)-8-[(diethylamino)methyl]-5,6,9,17,19-pentahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-1,2-dihydro-2,7-(epoxypentadeca[1,11,13]trienoimino)naphtho[2,1-b]furan-21-yl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: (14E,24E)-8-[(diethylamino)methyl]-5,6,9,17,19-pentahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-1,2-dihydro-2,7-(epoxypentadeca[1,11,13]trienoimino)naphtho[2,1-b]furan-21-yl acetate(4075-41-6)
• EPA Substance Registry System: (14E,24E)-8-[(diethylamino)methyl]-5,6,9,17,19-pentahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-1,2-dihydro-2,7-(epoxypentadeca[1,11,13]trienoimino)naphtho[2,1-b]furan-21-yl acetate(4075-41-6)

Safety Data

• Hazardous Substances Data: 4075-41-6(Hazardous Substances Data)

Usage

General Description

The chemical compound "(14E,24E)-8-[(diethylamino)methyl]-5,6,9,17,19-pentahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-1,2-dihydro-2,7-(epoxypentadeca[1,11,13]trienoimino)naphtho[2,1-b]furan-21-yl acetate" is a complex organic molecule with a long and intricate structure. It contains multiple functional groups including hydroxy, methoxy, and diethylamino groups, as well as a naphthofuran ring and an acetate moiety. The compound also has several stereocenters and conjugated double bonds. The specific biological or chemical properties of this compound are not mentioned in the name, so further information would be needed to fully understand its characteristics and potential applications.

Upstream product

• 13292-22-3 3-formylrifamycin SV 
• 109-89-7 diethylamine 
• 50-00-0 formaldehyd 
• 62623-68-1 rifamycin S 

Downstream Products

• 13292-22-3 3-Formyl-rifamycin SV 
• 13440-40-9 3-(Dimethoxy-methyl)-rifamycin SV 

Relevant articles and documents

3-N-substituted aminomethyl derivatives of rifamycin SV. A convenient method of synthesis, cyclization of certain derivatives, and anticellular and antiviral activities of several derivatives

A new synthesis of Mannich bases of rifamycin SV using the Borch procedure with rifaldehyde is described. This new synthesis offers two advantages over the previously published method. It provides a route to monoalkyl-aminomethylrifamycins (1e-h) and to unsubstituted aminomethylrifamycins that were not accessible by the old procedure. The new method also offers a preparative route to Mannich bases 1a and 1b which were needed in multigram quantities for biological testing. In addition, the cyclization of certain of the monoalkylaminomethylrifamycins to the novel N,15 didehydro 15 deoxo 3,15 epi[methano(alkylimino)]rifamycin SV derivatives is described. The anticellular and antiviral effects of representatives of both series of compounds against cultured mouse cells and murine oncornavirus are discussed.