4075-49-4 Usage
General Description
(24E)-5,6,9,17,19-pentahydroxy-8-{[(2-hydroxyethyl)(methyl)amino]methyl}-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-1,2-dihydro-2,7-(epoxypentadeca[1,11,13]trienoimino)naphtho[2,1-b]furan-21-yl acetate is a complex chemical compound found in nature. It is a derivative of naphthoquinone and contains multiple hydroxy and methyl groups. (24E)-5,6,9,17,19-pentahydroxy-8-{[(2-hydroxyethyl)(methyl)amino]methyl}-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-1,2-dihydro-2,7-(epoxypentadeca[1,11,13]trienoimino)naphtho[2,1-b]furan-21-yl acetate has a long and highly complex chemical structure that includes an epoxide and an acetate functional group. It is likely to possess significant pharmacological properties due to its intricate structure and is potentially valuable for research and therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 4075-49-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,0,7 and 5 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 4075-49:
(6*4)+(5*0)+(4*7)+(3*5)+(2*4)+(1*9)=84
84 % 10 = 4
So 4075-49-4 is a valid CAS Registry Number.
4075-49-4Relevant articles and documents
3-N-substituted aminomethyl derivatives of rifamycin SV. A convenient method of synthesis, cyclization of certain derivatives, and anticellular and antiviral activities of several derivatives
McCarthy,Moore,Wysong,Aldrich
, p. 1272 - 1276 (2007/10/21)
A new synthesis of Mannich bases of rifamycin SV using the Borch procedure with rifaldehyde is described. This new synthesis offers two advantages over the previously published method. It provides a route to monoalkyl-aminomethylrifamycins (1e-h) and to unsubstituted aminomethylrifamycins that were not accessible by the old procedure. The new method also offers a preparative route to Mannich bases 1a and 1b which were needed in multigram quantities for biological testing. In addition, the cyclization of certain of the monoalkylaminomethylrifamycins to the novel N,15 didehydro 15 deoxo 3,15 epi[methano(alkylimino)]rifamycin SV derivatives is described. The anticellular and antiviral effects of representatives of both series of compounds against cultured mouse cells and murine oncornavirus are discussed.
