407577-56-4Relevant academic research and scientific papers
Reactions of N- and C-alkenylanilines: I. Synthesis of anilides and amidines from ortho-alkenyl(cycloalkenyl)anilines and their transformations
Gataullin,Afon'kin,Fatykhov,Spirikhin,Abdrakhmanov
, p. 834 - 840 (2001)
N-Acetyl- and N-formyl-ortho-alkenyl(cycloalkenyl)anilines were synthesized. Their reaction with P2O, or PCl5 afforded quinolines. By reaction of the ortho-alkenyl(cycloalkenyl)anilines with 1-methylimino- or 1-phenylimino-1-chloroethanes amidines were obtained that were cyclized in the polyphosphoric acid. The reaction with the polyphosphoric acid of amidines prepared from alkenylanilines and 1-methylimino-1-chloroethane gave rise to 3-methyl-3,4-dihydroquinazolines; on replacing in the substrate methylimine group for phenylimine one the yield of quinazoline decreased.
Amidines: Synthesis from o-alkenylanilines and cyclization in polyphosphoric acid
Gataullin,Afon'kin,Ahdrakhmanov,Tolstikov
, p. 545 - 547 (2007/10/03)
Condensation of 2-[(E)-pent-3-en-2-yl]-4-, 2-[(E)-pent-2-en-2-yl]-4-, or 2-(cyclopent-1-enyl)-6-methylaniline with 1-chloro-1-(N-methylimino)-or 1-chloro-1-(N-phenylimino)ethane affords the corresponding amidines. Cyclization of the N-methylimino derivatives in polyphosphoric acid gives 3,4-dihydroquinazolines in high yields.
