407577-79-1

Upstream product

• 536-74-3 phenylacetylene 
• 407577-72-4 5-chloro-2-methyl-4-trifluoromethanesulfonyloxy-3(2H)-pyridazinone 
• 64178-82-1 5-chloro-4-hydroxy-2-methyl-2H-pyridazin-3-one 
• 77541-59-4 5-chloro-4-methoxy-2-methyl-3(2H)-pyridazinone 

Relevant academic research and scientific papers

New enediyne derivatives: Synthesis of symmetrically and unsymmetrically disubstituted 4,5-dialkynyl-3(2H)-pyridazinones

4,5-Dialkynyl-2-(methyl or phenyl)-3(2H)-pyridazinones (2a-c) were efficiently prepared via Sonogashira cross-coupling reaction on 4,5-dichloro-2-(methyl or phenyl)-3(2H)-pyridazinones (1a,b). Selective Sonogashira reactions were successfully achieved on