4076-57-7

Upstream product

• 106-42-3 para-xylene 
• 127-09-3 sodium acetate 
• 104-87-0 4-methyl-benzaldehyde 
• 558-13-4 carbon tetrabromide 

Downstream Products

• 4076-61-3 trans-1-methyl-2-(4-methylphenyl)cyclopropane 
• 4076-60-2 cis-1-methyl-2-p-CH₃-phenylcyclopropane 
• 622-47-9 4-tolylacetic acid 
• 91801-86-4 1ref-Aethyl-2trans-(p-tolyl)-cyclopropan 
• 91801-86-4 1ref-Aethyl-2cis-(p-tolyl)-cyclopropan 
• 93042-78-5 (+/-)1,1-Dimethyl-2-p-tolyl-cyclopropan 
• 18869-29-9 (E)-4,4'-dimethylstilbene 
• 6536-02-3 (E)-1,1'-(ethene-1,2-diylbis(4,1-phenylene))diethanone 
• 1121706-92-0 4-Nitrobenzyl (1S,5R,6S)-2-[6-(4-bromomethyl-benzyl)-7-methylthioimidazo[5,1-b]thiazolium-2-yl]-6-((1R)-1-hydroxyethyl,)-1-methyl-1-carbapen-2-em-3-carboxylate bromide 
• 105521-17-3 Triphenyl-(4-styrylbenzyl)phosphonium bromide 
• 64496-23-7 4,4'-distyrylstilbene 
• 50685-89-7 1-bromomethyl-4-styrylbenzene 
• 102593-85-1 1-Styryl-4-(4-brommethyl-styryl)-benzol 
• 51359-78-5 4-(bromomethyl)benzaldehyde 

Relevant academic research and scientific papers

Method for preparing trans-diphenylethylene compound

The invention relates to a preparation method of organic compounds and provides a method for preparing a trans-diphenylethylene compound. The method comprises adding a gem-dibromomethyl aromatic hydrocarbon compound, copper and polyamine into a reactor in the presence of a solvent, carrying out deoxidizing treatment, adding an oxygen-free water-free solvent into the reactor, carrying out a coupling reaction process to obtain C-C- double bonds, and carrying out separation and purification to obtain the trans-diphenylethylene compound. The method has mild synthesis conditions and has good reaction compatibility to different functional groups. The gem-dibromomethyl aromatic hydrocarbon compound as a raw material is easy to synthesize, may have different substituent groups and has a variable structure. The product obtained by coupling a raw material can be simply treated and has high purity. The asymmetric trans-diphenylethylene compound can be prepared from two different raw materials.

E-Stilbene derivatives synthesized by stereoselective reductive coupling of benzylic gem-dibromide promoted by Cu/polyamine

Stereoselective reductive coupling reaction of benzylic gem-dibromide promoted by Cu/polyamine produces E-stilbene derivatives with high yield under mild conditions. It provides a short pathway to synthesize symmetrical and asymmetrical E-stilbene derivatives using cheap reagents and alkenyl-free starting material together with easy workup.

Improved Halogenation of Methyl Aromatics and Methyl Heteroaromatics: Unexpected Reactivity of Tetrahalogeno-diphenylglycolurils

1,3,4,6-Tetrachloro (TCDGU) and 1,3,4,6-tetrabromo-3α,6α-diphenylglycolurils smooth halogen oxidizers have been exploited in a new direction as reagents for free radical substitution toward some N-halosuccinimide nonreactive bis-heterocycles. An unexpected selectivity and reactivity were observed with methyl benzenes, methyl heterocycles, and methyl-bis-heterocycles of interest. A chemometric study has been performed to optimize five independent factors of the chlorination reaction with TCDGU. The predictive model was established either for the halogenation conversion and the ratio of monochlorination.

Rasta resin-triphenylphosphine oxides and their use as recyclable heterogeneous reagent precursors in halogenation reactions

Heterogeneous polymer-supported triphenylphosphine oxides based on the rasta resin architecture have been synthesized, and applied as reagent precursors in a wide range of halogenation reactions. The rasta resin-triphenylphosphine oxides were reacted with either oxalyl chloride or oxalyl bromide to form the corresponding halophosphonium salts, and these in turn were reacted with alcohols, aldehydes, aziridines and epoxides to form halogenated products in high yields after simple purification. The polymersupported triphenylphosphine oxides formed as a byproduct during these reactions could be recovered and reused numerous times with no appreciable decrease in reactivity.

Thiol-activated gem-dithiols: A new class of controllable hydrogen sulfide donors

A class of novel thiol-activated H2S donors has been developed on the basis of the gem-dithiol template. These donors release H2S in the presence of cysteine or GSH in aqueous solutions as well as in cellular environments.

Benzylic Bromination-Acetoxylation of Toluenes by Bromide Ion Catalyzed Thermal Decomposition of Peroxydisulfate in Acetic Acid in the Presence of Acetate Ions

Side-chain bromination and acetoxylation of alkylaromatics by halide ion induced decomposition of potassium peroxydisulfate in acetic acid have been studied by product analysis techniques.Catalytic amounts of lithium bromide in the presence of sodium acetate were found effective in promoting benzylic bromination, followed by conversion to the corresponding benzyl acetates by reaction with acetate.The reaction is interpreted to take place by the redox and free-radical chain mechanism involving bromine atoms (ρ = -1.38 vs. ? + for substituted toluenes).In competiti ve experiments, benzyl and 4-nitrobenzyl acetates were found lees reactive than the corresponding toluenes in acetic acid with the couple S2O82-/Br- but more reactive in carbon tetrachloride with N-bromosuccinimide.

Conversion of Alcohols into Alkyl Bromides using Polymer-supported Triphenylphosphine Dibromide and Polymer-supported Triphenylphosphine and Carbon Tetrabromide

Alcohols were converted into alkyl bromides by reaction with polymer-supported triphenylphosphine dibromide and with polymer-supported triphenylphosphine and carbon tetrabromide.With both reagents excellent yields of bromides were obtained, but reaction with the latter reagent were faster and cleaner and in favourable cases high yields of bromide were obtained within 15 min at 20 deg C.An advantage of the polymer-supported reagents is that product isolation is facilitated by the ready separation of the supported from the non-supported species.

Sulfonation of aromatic compounds in the presence of solvents

A process for the sulfonation of aromatic compounds wherein an aromatic substance consisting of one or more aromatic compounds susceptible to the action of sulfur trioxide is formed into a reactant by admixture with one or more organic liquids, substantially inert to sulfur trioxide under the conditions of the process, which reactant is brought to boiling at a temperature not greater than 100° C under a pressure of from 0.1 mm Hg to atmospheric pressure, gaseous sulfur trioxide is introduced thereinto thereby causing it to continue to boil, the component or components of the reactant thus volatilized is or are reconverted to liquid in a heat-exchanger and recycled to the reaction chamber, and the pressure in the reaction chamber and the rate at which the gaseous sulfur trioxide is introduced into the reactant are controlled so as to ensure that there is always present in the reaction chamber an amount of volatilizable matter exceeding that amount volatilizable by the heat of reaction of the aromatic substance present in the reaction chamber with the gaseous sulfur trioxide in contact with said aromatic substance and that the temperature of the reaction mixture is a temperature of 100° C or below.