407617-08-7Relevant academic research and scientific papers
Synthesis of trisubstituted and tetrasubstituted alkenes via a manganate-induced migration-elimination process
Kakiya, Hirotada,Shinokubo, Hiroshi,Oshima, Koichiro
, p. 10063 - 10069 (2001)
Preparation of alkenes via a manganate-induced alkylation-elimination sequence was investigated. The reaction of 2-alkoxy-1,1-dibromoalkanes with trialkylmanganates afforded disubstituted or trisubstituted alkenes. Treatment of 2-alkoxy-1,1,1-tribromoalkanes with trialkylmanganates provided trisubstituted or tetrasubstituted alkenes through bromine-metal exchange, transfer of two alkyl groups from manganese to carbon, and successive elimination of metal and the β-alkoxy moieties.
