407629-44-1Relevant academic research and scientific papers
The C-terminal ester of membrane anchored peptide ion channels affects anion transport
Djedovic, Natasha,Ferdani, Riccardo,Harder, Egan,Pajewska, Jolanta,Pajewski, Robert,Schlesinger, Paul H.,Gokel, George W.
, p. 2862 - 2863 (2003)
Five heptapeptide derivatives, [CH3(CH2) 17]2NCO-CH2OCH2CO-Gly-Gly-Gly-Pr- Gly-Gly-Gly-OR, in which R = ethyl, 2-propyl, heptyl, benzyl, and cyclohexylmethyl, were found to transport chloride anion through a phospholipid bilayer to varying extents dependent on the identity of R. It was concluded that the R group is a membrane anchor for the synthetic chloride channels.
COMPOSITIONS AND METHODS FOR SYNTHETIC AMPHIPHILE-INDUCED CHANGES IN PLANT ROOT MORPHOLOGY
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, (2016/04/04)
The disclosure provides a method for increasing the lateral root development of a plant by exposing said plant to a composition containing a synthetic amphiphile. By increasing the number of lateral roots, the surface area of the root structure is increased, making the plants better able to survive such stresses as drought or low nutrients
Replacing proline at the apex of heptapeptide-based chloride ion transporters alters their properties and their ionophoretic efficacy
Schlesinger, Paul H.,Ferdani, Riccardo,Pajewska, Jolanta,Pajewski, Robert,Gokel, George W.
, p. 60 - 67 (2007/10/03)
A membrane anchored heptapeptide, (C18H37)2NHCOCH2OCH 2CO-NH-Gly-Gly-Gly-Pro-Gly-Gly-Gly-OCH2Ph, has proved to be a selective chloride anion transporter that functions in phospholipid bilay
SCMTR: A chloride-selective, membrane-anchored peptide channel that exhibits voltage gating
Schlesinger, Paul H.,Ferdani, Riccardo,Liu, Jun,Pajewska, Jolanta,Pajewski, Robert,Saito, Mitsuyoshi,Shabany, Hossein,Gokel, George W.
, p. 1848 - 1849 (2007/10/03)
The design, synthesis, and characterization of a synthetic chloride membrane transporter, SCMTR (synthetic chloride membrane transporter, "scimitar"), are presented. The compound [CH3(CH2)17]2NCOCH2OC
A hydrocarbon anchored peptide that forms a chloride-selective channel in liposomes.
Schlesinger, Paul H,Ferdani, Riccardo,Pajewski, Robert,Pajewska, Jolanta,Gokel, George W
, p. 840 - 841 (2007/10/03)
The heptapeptide sequence Gly-Gly-Gly-Pro-Gly-Gly-Gly, when anchored to diglycolic acid derived (C18H37)2NCOCH2OCH2COOH, forms chloride-selective ion channels in phospholipid liposomes but the related heptapeptide Gly-Gly-Gly-Leu-Gly-Gly-Gly, and tripepti
