40794-04-5 Usage
Uses
Used in Chemical Synthesis:
5-Chloro-2-methylanisole is used as a raw material in chemical synthesis for [application reason]. It is an essential component in the production of various chemical compounds, contributing to the development of new materials and products.
Used in Industrial Applications:
5-Chloro-2-methylanisole is used as a chemical intermediate in industrial applications for [application reason]. Its unique properties make it a valuable component in the manufacturing process, enhancing the efficiency and effectiveness of various industrial products.
Used in Scientific Research:
5-Chloro-2-methylanisole is used as a research compound in scientific applications for [application reason]. Its presence in laboratory settings allows scientists to study its properties and potential applications, furthering our understanding of chemistry and its practical uses.
Used in Pharmaceutical Development:
5-Chloro-2-methylanisole is used as a precursor in pharmaceutical development for [application reason]. Its role in the synthesis of pharmaceutical compounds makes it a crucial component in the creation of new drugs and treatments.
Used in Environmental Remediation:
5-Chloro-2-methylanisole is used as a reagent in environmental remediation for [application reason]. Its ability to interact with certain pollutants makes it a valuable tool in the process of cleaning up contaminated environments and protecting ecosystems.
Check Digit Verification of cas no
The CAS Registry Mumber 40794-04-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,7,9 and 4 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 40794-04:
(7*4)+(6*0)+(5*7)+(4*9)+(3*4)+(2*0)+(1*4)=115
115 % 10 = 5
So 40794-04-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H9ClO/c1-6-3-4-7(9)5-8(6)10-2/h3-5H,1-2H3
40794-04-5Relevant academic research and scientific papers
Pd-Catalyzed ipso, meta-Dimethylation of ortho-Substituted Iodoarenes via a Base-Controlled C-H Activation Cascade with Dimethyl Carbonate as the Methyl Source
Wu, Zhuo,Wei, Feng,Wan, Bin,Zhang, Yanghui
, p. 4524 - 4530 (2021/05/04)
A methyl group can have a profound impact on the pharmacological properties of organic molecules. Hence, developing methylation methods and methylating reagents is essential in medicinal chemistry. We report a palladium-catalyzed dimethylation reaction of ortho-substituted iodoarenes using dimethyl carbonate as a methyl source. In the presence of K2CO3 as a base, iodoarenes are dimethylated at the ipso- and meta-positions of the iodo group, which represents a novel strategy for meta-C-H methylation. With KOAc as the base, subsequent oxidative C(sp3)-H/C(sp3)-H coupling occurs; in this case, the overall transformation achieves triple C-H activation to form three new C-C bonds. These reactions allow expedient access to 2,6-dimethylated phenols, 2,3-dihydrobenzofurans, and indanes, which are ubiquitous structural motifs and essential synthetic intermediates of biologically and pharmacologically active compounds.
