40794-04-5

Usage

Uses

Used in Chemical Synthesis:
5-Chloro-2-methylanisole is used as a raw material in chemical synthesis for [application reason]. It is an essential component in the production of various chemical compounds, contributing to the development of new materials and products.
Used in Industrial Applications:
5-Chloro-2-methylanisole is used as a chemical intermediate in industrial applications for [application reason]. Its unique properties make it a valuable component in the manufacturing process, enhancing the efficiency and effectiveness of various industrial products.
Used in Scientific Research:
5-Chloro-2-methylanisole is used as a research compound in scientific applications for [application reason]. Its presence in laboratory settings allows scientists to study its properties and potential applications, furthering our understanding of chemistry and its practical uses.
Used in Pharmaceutical Development:
5-Chloro-2-methylanisole is used as a precursor in pharmaceutical development for [application reason]. Its role in the synthesis of pharmaceutical compounds makes it a crucial component in the creation of new drugs and treatments.
Used in Environmental Remediation:
5-Chloro-2-methylanisole is used as a reagent in environmental remediation for [application reason]. Its ability to interact with certain pollutants makes it a valuable tool in the process of cleaning up contaminated environments and protecting ecosystems.

InChI:InChI=1/C8H9ClO/c1-6-3-4-7(9)5-8(6)10-2/h3-5H,1-2H3

Upstream product

• 5306-98-9 5-chloro-2-methyl-phenol 
• 77-78-1 dimethyl sulfate 
• 136808-72-5 2-iodo-5-chlorophenol 
• 89-59-8 4-chloro-2-nitrotoluene 
• 95-79-4 5-chloro-2-methyl-benzenamine 

Downstream Products

• 859793-70-7 2-methoxy-4-phenoxy-toluene 
• 578-58-5 2-methylmethoxybenzene 
• 412021-93-3 1-(2-chloro-4-methoxy-5-methyl-phenyl)-ethanone 
• 76283-12-0 1-(bromomethyl)-4-chloro-2-methoxybenzene 
• 1021491-23-5 2-(2-chloro-4-methoxy-5-methylbenzyl)isoindoline-1,3-dione 
• 1044941-06-1 5-deutero-1-methoxy-2-methylbenzene 
• 78353-05-6 6-Chlor-4-methoxy-m-xylol 
• 95420-77-2 2-methoxy-4-phenoxybenzoic acid 
• 860000-88-0 2-hydroxy-4-phenoxy-benzoic acid 
• 858797-39-4 3-[5-(2-chloro-4-methoxy-5-methyl-phenyl)-[2]furyl]-propionic acid 
• 94169-56-9 2-chloro-3',4-dimethoxy-2',5-dimethylstilbene 
• 94169-55-8 2-chloro-3',4-dimethoxy-2',5-dimethylstilbene 
• 54278-83-0 micandrol-B 
• 54278-82-9 micandrol-A 

Relevant academic research and scientific papers

Pd-Catalyzed ipso, meta-Dimethylation of ortho-Substituted Iodoarenes via a Base-Controlled C-H Activation Cascade with Dimethyl Carbonate as the Methyl Source

A methyl group can have a profound impact on the pharmacological properties of organic molecules. Hence, developing methylation methods and methylating reagents is essential in medicinal chemistry. We report a palladium-catalyzed dimethylation reaction of ortho-substituted iodoarenes using dimethyl carbonate as a methyl source. In the presence of K2CO3 as a base, iodoarenes are dimethylated at the ipso- and meta-positions of the iodo group, which represents a novel strategy for meta-C-H methylation. With KOAc as the base, subsequent oxidative C(sp3)-H/C(sp3)-H coupling occurs; in this case, the overall transformation achieves triple C-H activation to form three new C-C bonds. These reactions allow expedient access to 2,6-dimethylated phenols, 2,3-dihydrobenzofurans, and indanes, which are ubiquitous structural motifs and essential synthetic intermediates of biologically and pharmacologically active compounds.