40807-10-1

Basic information

• Product Name: (E)-1-methyl-4-((4-nitrostyryl)sulfonyl)benzene
• Synonyms: (E)-1-methyl-4-((4-nitrostyryl)sulfonyl)benzene
• CAS NO: 40807-10-1
• Molecular Weight: 303.339
• Mol File: 40807-10-1.mol
• Article Data: 20

Chemical Properties

• CAS DataBase Reference: (E)-1-methyl-4-((4-nitrostyryl)sulfonyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-methyl-4-((4-nitrostyryl)sulfonyl)benzene(40807-10-1)
• EPA Substance Registry System: (E)-1-methyl-4-((4-nitrostyryl)sulfonyl)benzene(40807-10-1)

Safety Data

• Hazardous Substances Data: 40807-10-1(Hazardous Substances Data)

Upstream product

• 100-13-0 4-nitrostyrene 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 98-59-9 p-toluenesulfonyl chloride 
• 1950-78-3 p-toluenesulfonyl iodide 
• 937-31-5 (4-Nitrophenyl)acetylene 
• 28995-74-6 (E)-1-((2-iodo-2-(4-nitrophenyl)vinyl)sulfonyl)-4-methylbenzene 
• 882-06-4 4-nitro-trans-cinnamic acid 
• 2943-42-2 di(4-methyl)phenylthiosulfonate 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 
• 536-57-2 p-toluene sulfinic acid 
• 2216-24-2 3-(4-nitrophenyl)-2-propynoic acid 
• 41780-82-9 4-methyl-N'-(1-(4-nitrophenyl)ethylidene)benzenesulfonohydrazide 
• 619-89-6 p-nitrocinnamic acid 
• 555-16-8 4-nitrobenzaldehdye 

Downstream Products

• 902138-24-3 methyl 3-(4-nitrophenyl)-1H-pyrrole-2-carboxylate 

Relevant articles and documents

Copper-Catalyzed Heck-Type Couplings of Sulfonyl Chlorides with Olefins: Efficient and Rapid Access to Vinyl Sulfones

A copper-catalyzed redox-neutral alkene sulfonylation reaction has been developed. This reported protocol can be easily scale up to a gram scale, and smoothly applied to the late-stage modification of several bioactive molecules.

E -Selective synthesis of vinyl sulfones via silver-catalyzed sulfonylation of styrenes

An efficient and highly E-selective protocol for the synthesis of vinyl sulfones is described. This simple protocol demonstrates the first synthesis of vinyl sulfones via a silver-catalyzed C-S bond coupling reaction. In addition, the success of the reaction was found to be critically dependent on the use of TEMPO as the additive.

Green preparation method for vinyl sulfone derivative in aqueous phase

The invention relates to a green preparation method for a vinyl sulfone derivative in an aqueous phase. The method comprises the following steps: putting an olefin compound (1a), a sulfonyl hydrazidecompound of formula (2a) as shown in the specification, tetrabutylammonium iodide (TBAI), tert-butyl hydroperoxide (TBHP) and solvent water into a Schlenk reaction kettle, carrying out a stirring reaction on the reaction kettle at a certain temperature and an air atmosphere, monitoring the reaction process through TLC (Thin Layer Chromatography) or GC (Gas Chromatograph) till raw materials are completely reacted, and carrying out aftertreatment, thereby obtaining a target product, namely the vinyl sulfone derivative (I) as shown in the specification.