40815-75-6

Usage

Preparation

Preparation by reaction of allyl bromide on quinacetophenone with potassium carbonate in refluxing acetone (86%) or in refluxing methyl ethyl ketone (52%).

Upstream product

• 106-95-6 allyl bromide 
• 490-78-8 2,5-Dihydroxyacetophenone 

Downstream Products

• 90554-75-9 3-Hydroxy-1-<5-(allyloxy)-2-hydroxyphenyl>hexa-2,4-dien-1-one 
• 90554-76-0 (E)-But-2-enoic acid 2-acetyl-4-allyloxy-phenyl ester 
• 490-78-8 2,5-Dihydroxyacetophenone 
• 40815-79-0 2-acetyl-3-prop-2'-enyl-1,4-hydroquinone 
• 110295-18-6 3-<4-(2-Propenyl)cyclohexenyl>-3-hydroxy-1-<5-(allyloxy)-2-hydroxyphenyl>prop-2-en-1-one 
• 110295-20-0 (2Z,4E)-1-(5-Allyloxy-2-hydroxy-phenyl)-3-hydroxy-hepta-2,4,6-trien-1-one 
• 110295-21-1 (2Z,4E)-1-(5-Allyloxy-2-hydroxy-phenyl)-3-hydroxy-5-phenylsulfanyl-penta-2,4-dien-1-one 
• 110295-23-3 (2Z,4E)-1-(5-Allyloxy-2-hydroxy-phenyl)-3-hydroxy-5-(2-methyl-[1,3]dithiolan-2-yl)-penta-2,4-dien-1-one 
• 110295-16-4 3-[(Z)-3-(5-Allyloxy-2-hydroxy-phenyl)-1-hydroxy-3-oxo-propenyl]-benzoic acid methyl ester 
• 110295-17-5 4-[(Z)-3-(5-Allyloxy-2-hydroxy-phenyl)-1-hydroxy-3-oxo-propenyl]-benzoic acid methyl ester 
• 110295-22-2 (2Z,4E)-1-(5-Allyloxy-2-hydroxy-phenyl)-3-hydroxy-5-(2-methyl-[1,3]dithian-2-yl)-penta-2,4-dien-1-one 
• 110295-19-7 (2Z,4E)-1-(5-Allyloxy-2-hydroxy-phenyl)-3-hydroxy-6-methyl-hepta-2,4,6-trien-1-one 

Relevant academic research and scientific papers

Synthesis and biological evaluation of 3-styrylchromone derivatives as free radical scavengers and α-glucosidase inhibitors

A series of 3-styrylchromone derivatives (4-20) were synthesized and the structure-activity relationships for α-glucosidase inhibition and antioxidant activities were analyzed. Among the synthesized compounds, compounds 15 and 20, which contain a catechol moiety, showed both potent 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity (15: EC50 =17 μM; 20: EC50 =23 μM) and α-glucosidase inhibitory activity (15: IC50 =16 μM; 20: IC50 =10 μM). Our data suggest that 3-styrylchromone derivatives are novel α-glucosidase inhibitors that have the potential to counteract diet-induced hyperglycemia in diabetes.

Wacker oxidation methodology for the synthesis of the benzo-fused acetal core of marticin

Methodology for the synthesis of the benzo-fused acetal core of marticin is described in this paper. Condensation of readily available 1-(2-allyl-3,6- dimethoxyphenyl)ethanone with diethyl oxalate under Claisen condensation conditions furnished (Z)-ethyl

The synthesis of ventiloquinone L, the monomer of cardinalin 3

Readily available ethyl-4-acetoxy-6,8-dimethoxynaphthalene-2-carboxylate 27 was converted into 1 -[3-allyl-4(benzyloxy)-6,8-dimethoxy-2-naphthyl)-1-ethanol 31 in seven steps. Subjection of this compound to Wacker oxidation conditions provided 5-benzyloxy-

Benzofuran derivatives useful as inhibitors of mammalian leukotriene biosynthesis

Benzofuran derivatives, pharmaceutical compositions and methods of treatment are disclosed. These compounds are useful as inhibitors of mammalian leukotriene biosynthesis. As such, these compounds are useful therapeutic agents for treating allergic condit

Leukotriene receptor antagonists. 1. Synthesis and structure-activity relationships of alkoxyacetophenone derivatives

A series of derivatives of 2,4-dihydroxy-3-propylacetophenone were prepared and examined for their ability to block leukotriene D4 (LTD4) induced contraction of guinea pig ileum. Straight-chain carboxylic acids where the carboxyl gro