40815-79-0

Usage

Preparation

Preparation by thermal Claisen rearrangement of 5-(allyloxy)-2-hydroxyacetophenone without solvent at 200–220° (36%) or at 220–230° (74–75%).

Upstream product

• 40815-75-6 1-(5-allyloxy-2-hydroxyphenyl)-1-ethanone 
• 1125-55-9 2-Acetyl-1,4-benzoquinone 
• 762-73-2 trimethyl(allyl)stannane 
• 24850-33-7 allyltributylstanane 
• 490-78-8 2,5-Dihydroxyacetophenone 
• 762-72-1 allyl-trimethyl-silane 

Downstream Products

• 106627-41-2 2,5-dihydroxy-6-propylacetophenone 
• 174901-52-1 2-acetyl-3-prop-2'-enyl-1,4-dimethoxybenzene 
• 263138-74-5 2-allyl-6-benzyloxy-3-methoxyacetophenone 
• 263138-73-4 2-allyl-3-benzyloxy-6-methoxyacetophenone 
• 263138-76-7 1-(2-allyl-6-benzyloxy-3-methoxyphenyl)-1-ethanol 
• 263138-75-6 1-(2-allyl-3-benzyloxy-6-methoxyphenyl)-1-ethanol 
• 106627-19-4 6-(3-Acetyl-4-hydroxy-2-propyl-phenoxy)-hexanoic acid 
• 106627-32-1 diphenylmethyl 6-(3'-acetyl-4'-hydroxy-2'-propylphenoxy)hexanoate 
• 1392299-36-3 1-(2-allyl-3,6-dimethoxyphenyl)butane-1,4-diol 
• 1392299-38-5 1-(2-allyl-3,6-dimethoxyphenyl)-4-(tertbutyldimethylsilyloxy)-3-hydroxybutan-1-one 
• 1392299-32-9 ethyl (Z)-4-(2-allyl-3,6-dimethoxyphenyl)-2-hydroxy-4-oxobut-2-enoate 
• 1392299-33-0 ethyl 4-(2-allyl-3,6-dimethoxyphenyl)-2-hydroxy-4-oxobutanoate 
• 1392299-34-1 ethyl 4-[3,6-dimethoxy-2-(2-oxopropyl)phenyl]-2-hydroxy-4-oxobutanoate 
• 1392299-35-2 1-(2-allyl-3,6-dimethoxyphenyl)-3,4-dihydroxybutan-1-one 

Relevant academic research and scientific papers

Wacker oxidation methodology for the synthesis of the benzo-fused acetal core of marticin

Methodology for the synthesis of the benzo-fused acetal core of marticin is described in this paper. Condensation of readily available 1-(2-allyl-3,6- dimethoxyphenyl)ethanone with diethyl oxalate under Claisen condensation conditions furnished (Z)-ethyl

Convenient synthetic route to antimicrobial benzopyranquinones

A general synthetic strategy has been developed for the synthesis of racemic 3,4-dihydro-3-methyl-1H-benzopyran-5,8-dione 25, trans-(1R,3R)-5,8-dihydroxy-1,3-dimethyl-4-oxo-1H-benzopyran 39, rel (1R,3R,4R)-3,4-dihydro-1,3-dimethyl-4-hydroxy-1H-benzopyran-5,8-dione 41 and the rel-(4S)-diastereoisomer 42.

Leukotriene receptor antagonists. 1. Synthesis and structure-activity relationships of alkoxyacetophenone derivatives

A series of derivatives of 2,4-dihydroxy-3-propylacetophenone were prepared and examined for their ability to block leukotriene D4 (LTD4) induced contraction of guinea pig ileum. Straight-chain carboxylic acids where the carboxyl gro

Allylation of 2-Alkanoyl 1,4-Quinones with Allylsilanes and Allylstannanes. Efficient Synthesis of Pyranonaphthoquinone Antibiotics

Total syntheses of pyranonaphthoquinone antibiotics eleutherin, isoeleutherin, nanaomycin A, and deoxyfrenolicin are described.The crucial step in the route is a regioselective allylation of alkanoyl quinones with allylsilanes and allylstannanes.The allyl

LEWIS ACID MEDIATED ALLYLATION OF 2-ALKANOYL-1,4-QUINONES WITH ALLYLSILANE AND ALLYLSTANNANE

Allyltrimethylstannane reacts with 2-alkanoyl-1,4-quinones regioselectively to afford conjugate addition products which can be derived to 2-alkanoyl-3-allylhydroquinone diacetate, while allyltriphenylsilane reacts with the quinone to give naphthofuran.

Claisen Rearrangement of meta-Substituted Allyl Phenyl Ethers

Electron-releasing substituents at the 3-position of allyl phenyl ethers favour Claisen rearangement of the allyl group to the 6-position, whereas electron-acceptors favour migration to the 2-position. 2-Acylhydroquinone 4-allyl ethers yield, predominantly, the 3-allyl isomers, probably because internal hydrogen bonding confers naphthalenoid character on the aryl residue.