408316-48-3Relevant academic research and scientific papers
Synthesis of a novel diarylphosphinic acid: A distorted ground state mimic and transition state analogue for amide hydrolysis
Schuman, Marc,Lopez, Xabier,Karplus, Martin,Gouverneur, Véronique
, p. 10299 - 10307 (2001)
We describe herein the synthesis of a new unsymmetrical diarylphosphinic acid, a hapten aimed to produce catalytic antibodies for the hydrolysis of heterocyclic amides. The phosphinate functionality was selected as a mimic both of the tetrahedral intermed
