408334-96-3Relevant academic research and scientific papers
Studies on the chemistry and reactivity of α-substituted ketones in isonitrile-based multicomponent reactions
Fan, Lijun,Adams, Ashley M.,Polisar, Jason G.,Ganem, Bruce
scheme or table, p. 9720 - 9726 (2009/04/07)
(Chemical Equation Presented) Using the Passerini and Ugi reactions as representative tests, the utility of several α-substituted ketones R-CO-CH2-X (X = sulfonyloxy, acyloxy, azido, halo, hydroxy, and sulfonyl) in isonitrile-based multicompone
Multicomponent reaction design: a one-pot route to substituted di-O-acylglyceric acid amides from α-diazoketones
Fan, Lijun,Adams, Ashley M.,Ganem, Bruce
scheme or table, p. 5983 - 5985 (2009/04/11)
A four-component assembly of substituted di-O-acylglyceric acid amides has been developed from α-diazoketones. The process involves copper-catalyzed reaction of the α-diazoketone with a carboxylic acid, and subsequent Passerini condensation of the in situ formed α-acyloxyketone.
