40848-81-5Relevant academic research and scientific papers
Microwave-assisted synthesis of α-ethoxycarbamates
Lumbroso, Alexandre,Chevallier, Floris,Beaudet, Isabelle,Quintard, Jean-Paul,Besson, Thierry,Le Grognec, Erwan
experimental part, p. 9180 - 9187 (2010/01/16)
An efficient and reproducible synthesis of various α-ethoxycarbamates is described via a microwave heating mode. Compared to the thermal process, the microwave dielectric heating induces a dramatic reduction of the reaction time and the improvement of the
NMR detection of N-acyliminium ion intermediates generated from α-alkoxycarbamates
Yamamoto, Yoshinori,Nakada, Tomohisa,Nemoto, Hisao
, p. 121 - 125 (2007/10/02)
The N-acyliminium ion intermediates generated from α-alkoxycarbamates in the presence of Lewis acids were for the First time detected by 1 H and 13C NMR. It was confirmed that there is an equilibrium between the starting carbamate and the intermediate and that the equilibrium is highly dependent upon a Lewis acid. By using the saturation transfer method, the rate constant for the formation of the intermediate was obtained. NOE experiments revealed that ((4-methylphenyl)methylene)methyl(methoxycarbonyl)ammonium methyltrifluoroborate 6 has E-geometry.
