408526-00-1

Basic information

• Product Name: 1,3-diphenyl-1-(p-tolyl)prop-2-yn-1-ol
• Synonyms: 1,3-diphenyl-1-(p-tolyl)prop-2-yn-1-ol
• CAS NO: 408526-00-1
• Molecular Weight: 298.384
• Mol File: 408526-00-1.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: 1,3-diphenyl-1-(p-tolyl)prop-2-yn-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-diphenyl-1-(p-tolyl)prop-2-yn-1-ol(408526-00-1)
• EPA Substance Registry System: 1,3-diphenyl-1-(p-tolyl)prop-2-yn-1-ol(408526-00-1)

Safety Data

• Hazardous Substances Data: 408526-00-1(Hazardous Substances Data)

Upstream product

• 6738-06-3 phenylethynylmagnesium bromide 
• 134-84-9 4-Methylbenzophenone 
• 536-74-3 phenylacetylene 
• 1517-63-1 4-methylphenyl(phenyl)methanol 

Downstream Products

• 1192167-49-9 5,7-dimethyl-1,3-diphenyl-1-p-tolyl-1H-inden-6-ol 
• 1228391-02-3 1-phenyl-1-p-tolyl-3-(2,4,6-trimethoxyphenyl)-1H-indene 
• 1263098-43-6 2,5-diphenyl-4-(phenyl(p-tolyl)methyl)oxazole 
• 1263145-94-3 9-methyl-1,3-diphenyl-3-p-tolyl-3H-pyrrolo[1,2-a]indole 
• 1263145-99-8 9-ethyl-7-methyl-1,3-diphenyl-3-p-tolyl-3H-pyrrolo[1,2-a]indole 
• 1415035-01-6 3,5-diphenyl-5-(p-tolyl)-2-tosyl-2,5-dihydroisoxazole 
• 1415035-15-2 4-iodo-3,5-diphenyl-5-(p-tolyl)-2-tosyl-2,5-dihydroisoxazole 
• 1415035-28-7 4-bromo-3,5-diphenyl-5-(p-tolyl)-2-tosyl-2,5-dihydroisoxazole 
• 115037-08-6 4,5-diphenyl-3-(p-tolyl)-1H-pyrazole 
• 24052-18-4 3,5-diphenyl-4-(p-tolyl)-1H-pyrazole 
• 1450999-70-8 dimethyl 1-benzyl-4,6-diphenyl-6-(p-tolyl)-1,6-dihydropyridine-2,3-dicarboxylate 
• 1620975-23-6 (Z)-N-3-diphenyl-3-(p-tolyl)acrylamide 
• 1620975-24-7 (E)-N-3-diphenyl-3-(p-tolyl)acrylamide 

Relevant articles and documents

Gold-catalyzed tandem annulations of pyridylhomopropargylic alcohols with propargyl alcohols

A gold-catalyzed tandem annulation of propargylic alcohols and pyridylhomopropargylic alcohols is achieved, providing an atom-economical approach to a diverse set of polycyclic dihydrobenzofurans in good yields. The reaction proceeds via the 5-endo-dig cyclization/Meyer?Schuster rearrangement/Friedel?Crafts-type pathway. In this way, three C?C bonds and one C? O bond form to give a polycyclic skeleton in a one-pot process. Moreover, the products exhibit unique optical properties, which reveal their potential application value.

Synthesis of 1H-Pyrrolo[1,2-a]indoles via Lewis Acid-Catalyzed Annulation of Propargylic Alcohols with 2-Ethynylanilines

A novel highly efficient, environmentally benign Lewis acid-catalyzed, and protection-free protocol for the construction of valuable polycyclic products bearing a 1H-pyrrolo[1,2-a]indole scaffold is described, starting from readily available propargylic alcohols and 2-ethynylanilines. The one-pot transformation entails the cleavage of one C?O bond, and the construction of two C?N bonds and one C?C double bond. This unique operationally simple method is performed under mild conditions and in air, producing water as the only byproduct; it is scalable and demonstrates good functional group compatibility and broad scope.

Lewis Acid-Catalyzed Formal [3+3] Annulation of Propargylic Alcohols with 4-Hydroxy-2H-chromen-2-ones

A Lewis acid-catalyzed formal [3+3] cascade annulation strategy for the formation of diverse tricyclic compounds possessing functionalized pyrano[3,2-c]chromen-5(2H)-one fragments has been developed using propargylic alcohols and 4-hydroxy-2H-chromen-2-on