4086-61-7

Basic information

• Product Name: 2-(3,5-DIMETHYL-1H-PYRAZOL-1-YL)-4,6-DIMETHYLPYRIMIDINE
• Synonyms: TOSLAB 44992;2-(3,5-DIMETHYL-1H-PYRAZOL-1-YL)-4,6-DIMETHYLPYRIMIDINE;2-(3,5-Dimethylpyrazol-1-yl)-4,6-dimethylpyrimidine
• CAS NO: 4086-61-7
• Molecular Formula: C₁₁H₁₄N₄
• Molecular Weight: 202.26
• Mol File: 4086-61-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(3,5-DIMETHYL-1H-PYRAZOL-1-YL)-4,6-DIMETHYLPYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,5-DIMETHYL-1H-PYRAZOL-1-YL)-4,6-DIMETHYLPYRIMIDINE(4086-61-7)
• EPA Substance Registry System: 2-(3,5-DIMETHYL-1H-PYRAZOL-1-YL)-4,6-DIMETHYLPYRIMIDINE(4086-61-7)

Safety Data

• Hazardous Substances Data: 4086-61-7(Hazardous Substances Data)

Upstream product

• 23906-13-0 2-hydrazino-4,6-dimethylpyrimidine 
• 123-54-6 acetylacetone 
• 2582-30-1 aminoguanidine bicarbonate 
• 1937-19-5 1-aminoguanidine hydrochloride 
• 67-51-6 3,5-dimethyl-1H-pyrazole 
• 4472-44-0 2-chloro-4,6-dimethylpyrimidine 

Relevant articles and documents

Method For Producing Pyrimidinylpyrazole Compounds

The present invention provides a method for producing a pyrimidinylpyrazole compound (1), wherein aminoguanidine (2) or its salt is reacted with a β-diketone compound (3) to produce the pyrimidinylpyrazole compound: wherein R1 and R3 are each independently an alkyl group having 1 to 4 carbon atoms, and R2 is a hydrogen atom or an alkyl group having 1 to 4 carbon atoms. The method is excellent in the environmental compatibility and economic efficiency.

Utility of 2-hydrazino-4,6-dimethylpyridine in heterocyclic synthesis

2-Hydrazino-4,6-dimethylpyrimidine (1) readily underwent ring closure with benzoyl chloride to give 5,7-dimethyl-3 phenyl- 1,2,4-triazolo[4,3-a]pyrimidine (4a). Either N-benzoyl derivative (2) or the hydrazone (3a) can be used for formation of compound 4a. Reaction of compound 1 with acetylacetone gave the pyrazole derivative (6) rather than 1,2,4-triazepine derivative (5). The pyrrole (9) was the sole product from cyclization of 1 with 2,5 hexanedione. Reaction of compound 1 with carbon disulphide or ethyl chloroformate gave 1,2,4-triazolo[4,3-a]pyrimidines (10 and 12). The reaction of thiosemicarbazides (13 a-c) with ethyl bromoacetate and DCCD was investigated.