40863-27-2Relevant academic research and scientific papers
The carbomethylation of arylacrylamides leading to 3-ethyl-3-substituted indolin-2-one by cascade radical addition/cyclization
Dai, Qiang,Yu, Jintao,Jiang, Yan,Guo, Songjin,Yang, Haitao,Cheng, Jiang
, p. 3865 - 3867 (2014/04/03)
An FeCl2-promoted carbomethylation of arylacrylamides by di-tert-butyl peroxide (DTBP) is achieved, leading to 3-ethyl-3-substituted indolin-2-one in high yield. The reaction tolerates a series of functional groups, such as cyano, nitro, ethyloxy carbonyl, bromo, chloro, and trifluoromethyl groups. The radical methylation and arylation of the alkenyl group are involved in this reaction. This journal is the Partner Organisations 2014.
Pharmaceutical compounds
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, (2008/06/13)
A pharmaceutical compound of the formula STR1 and salts and esters thereof.
