40888-23-1Relevant academic research and scientific papers
Drawing from a pool of radicals for the design of selective enyne cyclizations
Mondal, Sayantan,Mohamed, Rana K.,Manoharan, Mariappan,Phan, Hoa,Alabugin, Igor V.
supporting information, p. 5650 - 5653 (2013/12/04)
Despite the possibility of intermolecular attack at four different locations, the Bu3Sn-mediated radical cyclization of aromatic enynes is surprisingly selective. The observed reaction path originates from the least stable of the equilibrating pool of isomeric radicals produced by intermolecular Bu3Sn attack at the π-bonds of substrates. The radical pool components are kinetically self-sorted via 5-exo-trig closure, the fastest of the four possible cyclizations. The resulting Sn-substituted indenes are capable of further transformations in reactions with electrophiles.
SYNTHESIS AND PROPERTIES OF BISDEHYDROANNULENEDIONES
Onishi, Yasunobu,Iyoda, Masahiko,Nakagawa, Masazumi
, p. 3641 - 3644 (2007/10/02)
Bisdehydro- and annulenediones have been synthesized by cyclic dimerization of corresponding ω-ethynyl acid chlorides in the presence of palladium-copper catalyst in triethylamine-benzene and fully characterized by analyses and their (1)H-NMR, mass, electronic and IR spectroscopic evidences.
