4089-98-9Relevant academic research and scientific papers
Visible Light-Induced Decarboxylative Alkylation of Heterocyclic Aromatics with Carboxylic Acids via Anthocyanin as a Photocatalyst
Guo, Rui,Zuo, Minghui,Tian, Qinye,Hou, Chuanfu,Sun, Shouneng,Guo, Weihao,Wu, Hongfeng,Chu, Wenyi,Sun, Zhizhong
, p. 1976 - 1981 (2020/06/01)
A visible light-induced decarboxylative alkylation of heterocyclic aromatics with aliphatic carboxylic acids was developed by using anthocyanins as a photocatalyst under mild conditions. A series of alkylated heterocyclic compounds were obtained in modera
Stereoselective chemoenzymatic synthesis of enantiopure 1-(Heteroaryl)ethanamines by lipase-Catalysed kinetic resolutions
Alatorre-Santamaria, Sergio,Gotor-Fernandez, Vicente,Gotor, Vicente
experimental part, p. 2533 - 2538 (2009/09/25)
The efficient chemical synthesis and enzymatic kinetic resolution of a family of 1-(heteroaryl)ethanamines have been performed with lipases responsible for the preparation of nitrogenated compounds in high optical purity. Thus, Candida antarctica lipase type B has been identified as an excellent biocatalyst for the stereoselective production of the corresponding enantiomerically enriched (B)-acetamides and (S)-amines. A similar effect of the heteroatom in the cyclic ring has been observed in terms of reactivity and enantio- selectivity, with benzoxazole, benzothiazole and benzimidazole derivatives being obtained with excellent enantiopurities after one day of reaction. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009.
