40901-46-0

Usage

Properties

Colored dye, fluorescent stain for cell imaging and microscopy, antimicrobial, antifungal

Potential Applications

Development of new antibiotics, photodynamic therapy for cancer treatment

Further Research

Needed to fully understand therapeutic potential and safety profile

Upstream product

• 117-80-6 2,3-Dichloro-1,4-naphthoquinone 
• 95-54-5 1,2-diamino-benzene 
• 1526-73-4 3-chloro-2-hydroxy-naphthalene-1,4-dione 
• 18099-99-5 3-chloro-1,2-naphthoquinone 

Downstream Products

• 61316-12-9 N-benzo[a]phenazin-5-yl-benzene-1,2-diamine 
• 61316-14-1 N-(2-benzo[a]phenazin-5-ylamino-phenyl)-toluene-4-sulfonamide 
• 61316-66-3 N-(2-benzo[a]phenazin-5-ylamino-phenyl)-acetamide 

Relevant academic research and scientific papers

Micelles catalyzed one pot regio- and chemoselective synthesis of benzo[a]phenazines and naphtho[2,3-d]imidazoles 'in H2O'

An efficient, novel, and concise one pot regio- and chemoselective synthesis of benzo[a]phenazines (4) and naphtho[2,3-d]imidazoles (8) has been accomplished in excellent yields by nucleophilic substitution reaction of 2,3-dichloro-1,4-naphthoquinone (1) with o-phenylenediamine (2) and benzamidines (7) respectively 'in H2O' using base and micelles (SDS) as catalyst. Analog reaction of 2,3-dichloro-1,4-naphthoquinone (1) with 2-aminobenzenethiol (9) under identical conditions led to formation of a mixture of benzo[b]phenothiazine (10), benzo[a]phenothiazine (11), and benzo[a]-1,4-benzothiazino-3,2-phenothiazine (12) in 17%, 23%, and 57% yields, respectively.

Novel Chromophoric Heterocycles Based on Maleimide and Naphthoquinone

1-Phenyl-3,4-dichloromaleimide, 1-n-propyl-3-bromomaleimide, and 2,3-dichloro-1,4-naphthoquinone have been condensed with various mono- and bis-nucleophiles to yield a range of novel dyes and pigments.Their visible absorption spectra are discussed.