40916-73-2Relevant articles and documents
3,3-DISUBSTITUTED-1-HYDROXYTRIAZ-1-ENE 2-OXIDES AND WOUND-HEALING COMPOSITIONS USING THEM
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Paragraph 0045, (2015/08/03)
Esters, carbonates and imides of 3,3-disubstituted-1-hydroxytriaz-1-ene 2-oxides of the formula I are disclosed. The compounds release nitric oxide (NO) under physiologic conditions, and pharmaceutical compositions containing them are useful to aid in wound healing.
2,3-DIHYDROIMIDAZOL[1,2-C]PYRIMIDIN-5(1H)-ONE BASED LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 (LP-PLA2) INHIBITORS
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Page/Page column 32, (2014/08/07)
The present invention relates to novel compounds that inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease.
Synthesis of pacidamycin analogues via an Ugi-multicomponent reaction
Okamoto, Kazuya,Sakagami, Masahiro,Feng, Fei,Takahashi, Fumiyo,Uotani, Kouichi,Togame, Hiroko,Takemoto, Hiroshi,Ichikawa, Satoshi,Matsuda, Akira
scheme or table, p. 4810 - 4815 (2012/08/13)
The second-generation synthesis of 3′-hydroxypacidamycin D (2) has been accomplished via an Ugi-four component reaction at a late stage of the synthesis. This approach provided ready access to a range of analogues including diastereomers of the diaminobut