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N'-(2-(1H-indol-3-yl)acetyl)-4-methylbenzenesulfonohydrazide is a complex organic compound with the chemical formula C16H16N2O3S. It is a derivative of indole, a heterocyclic aromatic organic compound, and benzenesulfonohydrazide, a compound containing a benzene ring and a sulfonyl group. This molecule features a sulfonylhydrazide group attached to a 4-methylbenzene ring, which is further connected to an indole-3-ylacetyl moiety. The compound is known for its potential applications in pharmaceutical research, particularly in the development of drugs targeting various biological processes. Its structure and properties make it a subject of interest for chemists and biologists studying the interactions of such molecules with biological targets.

4092-13-1

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4092-13-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 4092-13-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,0,9 and 2 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 4092-13:
(6*4)+(5*0)+(4*9)+(3*2)+(2*1)+(1*3)=71
71 % 10 = 1
So 4092-13-1 is a valid CAS Registry Number.

4092-13-1Downstream Products

4092-13-1Relevant academic research and scientific papers

Design and synthesis of new dual binding site cholinesterase inhibitors: In vitro inhibition studies with in silico docking

Yar, Muhammad,Bajda, Marek,Mehmood, Rana Atif,Sidra, Lala Rukh,Ullah, Nisar,Shahzadi, Lubna,Ashraf, Muhammad,Ismail, Tayaba,Shahzad, Sohail Anjum,Khan, Zulfiqar Ali,Naqvi, Syed Ali Raza,Mahmood, Nasir

, p. 331 - 338 (2014)

Cholinesterases (ChEs) play a vital role in the regulation of cholinergic transmission. The inhibition of ChEs is considered to be involved in increasing acetylcholine level in the brain and thus has been implicated in the treatment of Alzheimer's disease. We have designed and synthesized a series of novel indole derivatives and screened them for inhibition of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). Most of the tested compounds exhibited inhibitory activity against AChE and BChE. Among them 4f and 6e showed the highest AChE inhibitory activity with IC50 91.21±0.06 and 68.52±0.04 μM, respectively. However compound 5a exhibited the highest inhibitory activity against BChE (IC50 55.21±0.12 μM).

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