409335-11-1Relevant academic research and scientific papers
Synthesis of the enantiomers of 1-{2-Hydroxy-3-[4-(2-hydroxy-phenyl)- piperazin-1-yl ]-propyl}-pyrrolidin-2-one using soluble and polystyrene bound salenCo(III)OAc complexes as catalysts of hydrolytic kinetic resolution
Kulig,Nowicki,Malawska
, p. 179 - 186 (2008/02/11)
The asymmetric synthesis of 1-{2-hydroxy-3-[4-(2-hydroxy-phenyl)-piperazin- 1-yl]-propyl}-pyrrolidin-2-one 3 is described. Enantiomers of compound 3 were synthesized by hydrolytic kinetic resolution (HKR) of racemic 1-oxiranylmethyl-pyrrolidin-2-one rac-2
