17201-66-0

Usage

Type of Compound

Lactam and cyclic ether

Structural Components

Contains a pyrrolidinone and oxirane moiety

Usage

Building block in organic synthesis

Applications

Production of pharmaceuticals and agrochemicals

Additional Uses

Reactant in preparation of compounds with biological activities

Other Applications

Polymer science and materials chemistry

Safety Precaution

Handle with caution due to potential health and safety hazards

InChI:InChI=1/C7H11NO2/c9-7-2-1-3-8(7)4-6-5-10-6/h6H,1-5H2/t6-/m1/s1

Upstream product

• 616-45-5 2-pyrrolidinon 
• 106-89-8 epichlorohydrin 

Downstream Products

• 148274-76-4 N-(beta-Hydroxy-gamma-(N-phenylpiperazinepropyl))-2-pyrrolidinone 
• 409335-13-3 (R)-(-)-1-(2,3-epoxypropyl)-pyrrolidin-2-one 
• 409335-14-4 (S)-(+)-1-(2,3-epoxypropyl)-pyrrolidin-2-one 
• 470676-53-0 1-{2-hydroxy-3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-pyrrolidin-2-one 
• 409335-12-2 (S)-(+)-1-(2,3-dihydroxypropyl)-pyrrolidin-2-one 
• 409335-11-1 (R)-(-)-1-(2,3-dihydroxypropyl)-pyrrolidin-2-one 
• 944402-63-5 1-{3-[4-(2-ethoxyphenyl)piperazin-1-yl]-2-hydroxypropyl}-pyrrolidin-2-one 
• 763915-83-9 1-{2-hydroxy-3-[4-(2-trifluoromethylphenyl)piperazin-1-yl]-propyl}pyrrolidin-2-one 
• 944402-67-9 1-{2-hydroxy-3-[4-(3-hydroxyphenyl)piperazin-1-yl]propyl}pyrrolidin-2-one 
• 952719-71-0 C₁₅H₂₃N₃O₂ 
• 944402-69-1 1-{2-hydroxy-3-[4-(3-methoxyphenyl)piperazin-1-yl]propyl}pyrrolidin-2-one 

Relevant academic research and scientific papers

POLYALKYLENE GLYCOL-CONTAINING COMPOUND

The present invention provides a polyalkylene glycol-containing compound having higher detergency than conventional polyalkylene glycol-containing compounds. The present invention relates to a polyalkylene glycol-containing compound represented by the following formula (1-1).

Synthesis and pharmacological evaluation of new 1-[3-(4-phenylpiperazin-1- yl)-propyl]- and 1-[3-(4-phenylpiperidine)-propyl]- 3-aryl-3-alkyl-pyrrolidin-2- one derivatives with antiarrhythmic and antihypertensive activity

A series of novel phenylpiperazine and phenylpiperidine derivatives bearing a 3,3-disubstituted pyrrolidin-2-one fragment were synthesized and evaluated for their binding affinity for α1-adrenoceptors (ARs) and for their antiarrhythmic and anti

Synthesis of the enantiomers of 1-{2-Hydroxy-3-[4-(2-hydroxy-phenyl)- piperazin-1-yl ]-propyl}-pyrrolidin-2-one using soluble and polystyrene bound salenCo(III)OAc complexes as catalysts of hydrolytic kinetic resolution

The asymmetric synthesis of 1-{2-hydroxy-3-[4-(2-hydroxy-phenyl)-piperazin- 1-yl]-propyl}-pyrrolidin-2-one 3 is described. Enantiomers of compound 3 were synthesized by hydrolytic kinetic resolution (HKR) of racemic 1-oxiranylmethyl-pyrrolidin-2-one rac-2