17201-66-0

Basic information

• Product Name: 1-(2-OXIRANYLMETHYL)-2-PYRROLIDINONE
• Synonyms: 1-(2-OXIRANYLMETHYL)-2-PYRROLIDINONE
• CAS NO: 17201-66-0
• Molecular Formula: C₇H₁₁NO₂
• Molecular Weight: 141.17
• Mol File: 17201-66-0.mol
• Article Data: 4

Chemical Properties

• Melting Point: 118-124°C
• Boiling Point: 289.2°C at 760 mmHg
• Flash Point: 128.7°C
• Appearance: /
• Density: 1.236g/cm³
• Vapor Pressure: 0.00223mmHg at 25°C
• Refractive Index: 1.537
• CAS DataBase Reference: 1-(2-OXIRANYLMETHYL)-2-PYRROLIDINONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-OXIRANYLMETHYL)-2-PYRROLIDINONE(17201-66-0)
• EPA Substance Registry System: 1-(2-OXIRANYLMETHYL)-2-PYRROLIDINONE(17201-66-0)

Safety Data

• Hazardous Substances Data: 17201-66-0(Hazardous Substances Data)

Usage

General Description

1-(2-Oxiranylmethyl)-2-pyrrolidinone, also known as N-((2-hydroxyethyl)methyl)oxiranecarboxamide, is a chemical compound with the molecular formula C7H11NO2. It is a lactam and a cyclic ether that contains both a pyrrolidinone and oxirane moiety. 1-(2-OXIRANYLMETHYL)-2-PYRROLIDINONE is commonly used as a building block in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals. It is also used as a reactant in the preparation of various compounds with biological activities. Additionally, it is known to have applications in polymer science and materials chemistry. Despite its potential usefulness, it is important to handle this compound with caution, as it may pose various health and safety hazards if mishandled.

InChI:InChI=1/C7H11NO2/c9-7-2-1-3-8(7)4-6-5-10-6/h6H,1-5H2/t6-/m1/s1

Upstream product

• 616-45-5 2-pyrrolidinon 
• 106-89-8 epichlorohydrin 

Downstream Products

• 470676-53-0 1-{2-hydroxy-3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-pyrrolidin-2-one 
• 409335-13-3 (R)-(-)-1-(2,3-epoxypropyl)-pyrrolidin-2-one 
• 409335-14-4 (S)-(+)-1-(2,3-epoxypropyl)-pyrrolidin-2-one 
• 409335-12-2 (S)-(+)-1-(2,3-dihydroxypropyl)-pyrrolidin-2-one 
• 409335-11-1 (R)-(-)-1-(2,3-dihydroxypropyl)-pyrrolidin-2-one 
• 1262099-39-7 1-(2-hydroxy-3-(4-phenylpiperidin-1-yl)propyl)pyrrolidin-2-one 
• 944402-71-5 1-{3-[4-(2,4-difluorophenyl)piperazin-1-yl]-2-hydroxypropyl}pyrrolidin-2-one 
• 952795-52-7 1-{3-[4-(5-chloro-2-methoxyphenyl)piperazin-1-yl]-2-hydroxypropyl}pyrrolidin-2-one 
• 944402-61-3 1-{3-[4-(2-fluorophenyl)piperazin-1-yl]-2-hydroxypropyl}pyrrolidin-2-one 
• 944402-69-1 1-{2-hydroxy-3-[4-(3-methoxyphenyl)piperazin-1-yl]propyl}pyrrolidin-2-one 
• 952719-71-0 C₁₅H₂₃N₃O₂ 
• 944402-67-9 1-{2-hydroxy-3-[4-(3-hydroxyphenyl)piperazin-1-yl]propyl}pyrrolidin-2-one 
• 763915-83-9 1-{2-hydroxy-3-[4-(2-trifluoromethylphenyl)piperazin-1-yl]-propyl}pyrrolidin-2-one 
• 944402-63-5 1-{3-[4-(2-ethoxyphenyl)piperazin-1-yl]-2-hydroxypropyl}-pyrrolidin-2-one 

Relevant articles and documents

POLYALKYLENE GLYCOL-CONTAINING COMPOUND

The present invention provides a polyalkylene glycol-containing compound having higher detergency than conventional polyalkylene glycol-containing compounds. The present invention relates to a polyalkylene glycol-containing compound represented by the following formula (1-1).

Synthesis of the enantiomers of 1-{2-Hydroxy-3-[4-(2-hydroxy-phenyl)- piperazin-1-yl ]-propyl}-pyrrolidin-2-one using soluble and polystyrene bound salenCo(III)OAc complexes as catalysts of hydrolytic kinetic resolution

The asymmetric synthesis of 1-{2-hydroxy-3-[4-(2-hydroxy-phenyl)-piperazin- 1-yl]-propyl}-pyrrolidin-2-one 3 is described. Enantiomers of compound 3 were synthesized by hydrolytic kinetic resolution (HKR) of racemic 1-oxiranylmethyl-pyrrolidin-2-one rac-2