4094-90-0

Upstream product

• 4039-82-1 Benzyl propargyl ether 
• 100-39-0 benzyl bromide 

Downstream Products

• 1573119-08-0 4-[(phenylmethoxy)methyl-1-(4-bromobenzyl)]-1H-1,2,3-triazole 
• 1049744-08-2 4-[(phenylmethoxy)methyl]-1-(benzyl)-1H-1,2,3-triazole 
• 1403848-76-9 3-(4-(benzyloxy)-1-(4-methoxyphenyl)but-2-yn-1-yl)-1-methyl-1H-indole 
• 1313514-13-4 (4-(benzyloxy)-1,1-difluorobut-2-ynylsulfonyl)benzene 
• 219631-28-4 1,6-bis(benzyloxy)hexa-2,4-diyne 
• 109872-98-2 5-Benzyloxy-2,2-difluoro-pent-3-ynoic acid methyl ester 

Relevant academic research and scientific papers

β-CD/CuI catalyzed regioselective synthesis of iodo substituted 1,2,3-triazoles, imidazo[1,2-a]-pyridines and benzoimidazo[2,1-b]thiazoles in water and their functionalization

An environment benign process has been developed for the regioselective synthesis of 5-iodo-1,4-disubstituted-1,2,3-triazoles catalyzed by CuI/β-CD in water. Moreover, the process was manifested for the efficient synthesis of 2-iodo-imidazo[1,2-a]pyridine

Pd(0)-catalyzed iodoalkynation of norbornene scaffolds: The remarkable solvent effect on reaction pathway

A palladium-catalyzed iodoalkynation of norbornene has been realized with the use of alkynyl iodides 1, which is found to be strongly solventdependent. MeCN favors 1,7-iodoalkylation product 3 while CCl4 leads to 1,2-iodoalkylation product 4.

Mild and efficient oxy-iodination of alkynes and phenols with potassium iodide and tert-butyl hydroperoxide

An efficient synthesis of 1-iodoalkynes and iodophenols was easily achieved by employing simple KI and TBHP. The reaction does not involve the use of a metal and base combination. A variety of substituted alkynes and phenols were prepared with good to excellent yield.

3,3-difluoro-1-iodocyclopropenes: A simple synthesis and their reactions

The [1 + 2] cycloaddition reaction of 1-iodoalkynes with difluorocarbene, generated from the decomposition of FSO2CF2COOSiMe3 in diglyme in the presence of 10 mol % NaF at 120 °C, gives 3,3-difluoro-1-iodocyclopropenes in good yields. These new iodides can be trifluoromethylated and functionalized via the Heck reaction. The unusual hydrolytic reactions of the iodides under acidic conditions was also investigated.

A simple convenient method for the synthesis of 1-iodoalkynes

Reaction of terminal alkynes with ethylmagnesium bromide in THF followed by the addition of iodine in THF gives 1-iodoalkynes in excellent yields (90-96%).