4095-02-7Relevant articles and documents
(±)-2-oxocyclohexanepropionic acid: Dual conformational selection and hydrogen bonding in a δ-keto acid, and a two-phase technique for crystallizing acids by contact with aqueous solutions of their salts
Lalancette, Roger A.,Thompson, Hugh W.
, p. o638-o640 (2003)
The asymmetric unit of the title compound, C9H14O3, consists of two molecules having conformations that differ by 121.7 (4)° in their rotation about the equatorial substituent bond, so that the side chain extends away from
Microwave promoted regeneration of carbonyl compounds from oximes using N, N-dichloro poly(styrene-co-divinylbenzene)sulphonamide resin
Beldar,Sharma, Mamta
experimental part, p. 288 - 292 (2012/02/01)
An efficient, economically viable and operationally simple method was developed for deoximation of oximes (of ketones and aldehydes) to their corresponding carbonyl compounds using polymer beads of N, N-dichloro poly(styrene-co-divinylbenzene)sulphonamide resin. Polymeric reagent offered speedy conversion and substantial yields of products under mild condition and is recyclable. Deoximation was monitored by the use of 13C NMR.
Total synthesis of the marine alkaloid (±)-lepadiformine via a radical carboazidation
Schaer, Pascal,Renaud, Philippe
, p. 1569 - 1571 (2007/10/03)
The total synthesis of lepadiformine has been achieved in 10 steps and 15% overall yield from cyclohexanone. The amino-substituted quaternary carbon center is created through a radical carboazidation reaction. The tricyclic core of lepadiformine is built via an efficient hydrogenation process, involving reduction of the azide and intramolecular reductive amination of a ketone, followed by lactamization of the intermediate γ-aminoester. The hydroxymethyl side chain is introduced according to a modified Takahata procedure after conversion of the lactam into a thiolactam.
