40950-04-7

Upstream product

• 97-00-7 1-chloro-2,4-dinitro-benzene 
• 94-09-7 p-aminoethylbenzoate 
• 59-46-1 Procaine 
• 70-34-8 2,4-Dinitrofluorobenzene 

Downstream Products

• 15127-76-1 4-(2-amino-4-nitrophenylamino)benzoic acid ethyl ester 
• 149651-23-0 3-(2,4-dinitro-anilino)-benzoic acid ethyl ester 

Relevant academic research and scientific papers

Synthesis and microbiological evaluation of several benzocaine derivatives

Starting from benzocaine, a well-known anaesthetic, ten derivatives were synthesized and characterized by UV-vis, IR, NMR, and elemental analysis. Most of the compounds contain residues with recognized biological activity, like nicotinic acid (vitamin B3 or PP), biotin (vitamin B7 or H), lipoic acid (thioctic acid), adamantine, as well as other residues of crown-ether type, benzofurazane, naphtylurea, di- and tri-nitrobenzene, and a nitroxide radical. The biological evaluation of the obtained compounds included hydrophobicity (lipophobicity) assay, total antioxidant and microbiological activity tests.

Quinoxaline-phosphonic acid derivatives

The disclosure relates to quinoxaline derivatives of Formula I wherein R1, R4, R5, R6, R7 and R8 are as defined in the disclosure, as well as their production and use in medicinal agents.