4098-31-1 Usage
Uses
Used in Pharmaceutical Industry:
2-(Chloromethyl)-5-nitro-furan is used as a synthetic intermediate for the development of various pharmaceuticals. Its unique structure allows for the creation of a wide range of bioactive compounds, contributing to the discovery of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 2-(Chloromethyl)-5-nitro-furan serves as a key intermediate in the synthesis of agrochemicals. Its reactivity and functional groups enable the production of compounds with pesticidal properties, aiding in the development of effective crop protection agents.
Used in Fine Chemicals Industry:
2-(Chloromethyl)-5-nitro-furan is utilized as a precursor in the synthesis of fine chemicals. Its versatility in organic reactions facilitates the production of specialty chemicals used in various applications, such as fragrances, dyes, and other industrial chemicals.
Safety Note:
It is crucial to handle 2-(Chloromethyl)-5-nitro-furan with care due to its toxic nature. Exposure can cause irritation to the skin, eyes, and respiratory system. Proper safety measures, including the use of personal protective equipment and adherence to safety protocols, are essential when working with 2-(chloromethyl)-5-nitro-furan.
Check Digit Verification of cas no
The CAS Registry Mumber 4098-31-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,0,9 and 8 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 4098-31:
(6*4)+(5*0)+(4*9)+(3*8)+(2*3)+(1*1)=91
91 % 10 = 1
So 4098-31-1 is a valid CAS Registry Number.
InChI:InChI=1/C5H4ClNO3/c6-3-4-1-2-5(10-4)7(8)9/h1-2H,3H2
4098-31-1Relevant academic research and scientific papers
NOVEL COMPOUND, ORGANIC CATION TRANSPORTER 3 DETECTION AGENT, AND ORGANIC CATION TRANSPORTER 3 ACTIVITY INHIBITOR
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Paragraph 0874-0875; 0878, (2016/08/17)
[Problem] The present invention addresses the problem of providing a novel compound. The present invention also addresses the problem of providing an OCT3 detection agent or an OCT3 activity inhibitor, which comprises the novel compound. [Solution] A compound represented by formula (A), a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable solvate thereof. ????????R1-R2-R3-R4?????(A)
5-Nitrofuran-2-ylmethyl group as a potential bioreductively activated pro-drug system
Berry, Jane M.,Watson, Corrine Y.,Whish, William J. D.,Threadgill, Michael D.
, p. 1147 - 1156 (2007/10/03)
5-Substituted isoquinolin-1-ones have been synthesised by one-pot Curtius rearrangement of the corresponding substituted 3-phenylpropenoyl azides and cyclisation. Arylmethylation of the anions of the isoquinolinones with benzyl halides [4-methoxybenzyl chloride, 2-(chloromethyl)furan and 5-nitro-2-(tosyloxymethyl)furan] takes place exclusively at nitrogen. Nitration of 2-(furan-2-ylmethyl)isoquinolin-1-one in strongly acidic medium gives 2-(5-nitrofuran-2-ylmethyl)isoquinolin-1-one, whereas weaker acidic conditions lead to dinitration. Curtius rearrangement of 3-carboranylbutanoyl azide and trapping with 5-nitrofuran-2-ylmethanol gives 5-nitrofuran-2-ylmethyl N-(3-carboranylpropyl)carbamate. Biomimetic reduction of these nitrofuranylmethyl derivatives of anticancer drugs triggers release of the parent drugs. Thus, these nitrofurans have potential applications as pro-drugs for selective release of therapeutic drugs in hypoxic solid tumours.
