410086-25-8 Usage
Uses
Used in Medicinal Chemistry:
1(2H)-Isoquinolinone,5-fluoro-(9CI) is used as a building block for the synthesis of pharmaceuticals and agrochemicals. The introduction of a fluorine atom can enhance the compound's lipophilicity, metabolic stability, and binding affinity to target proteins, leading to improved drug efficacy and selectivity.
Used in Research and Development:
1(2H)-Isoquinolinone,5-fluoro-(9CI) serves as a valuable research tool in the study of biological systems. Its unique structure and properties allow scientists to investigate the effects of fluorine substitution on molecular interactions, enzyme inhibition, and receptor binding. This knowledge can contribute to the design of novel therapeutic agents and a better understanding of biological processes.
Check Digit Verification of cas no
The CAS Registry Mumber 410086-25-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,1,0,0,8 and 6 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 410086-25:
(8*4)+(7*1)+(6*0)+(5*0)+(4*8)+(3*6)+(2*2)+(1*5)=98
98 % 10 = 8
So 410086-25-8 is a valid CAS Registry Number.
410086-25-8Relevant academic research and scientific papers
Rhodium(III)-catalyzed C-H activation/annulation with vinyl esters as an acetylene equivalent
Webb, Nicola J.,Marsden, Stephen P.,Raw, Steven A.
, p. 4718 - 4721 (2015/04/27)
The behavior of electron-rich alkenes in rhodium-catalyzed C-H activation/annulation reactions is investigated. Vinyl acetate emerges as a convenient acetylene equivalent, facilitating the synthesis of sixteen 3,4-unsubstituted isoquinolones, as well as select heteroaryl-fused pyridones. The complementary regiochemical preferences of enol ethers versus enol esters/enamides is discussed.
Hepatitis C Virus Inhibitors
-
Page/Page column 137, (2008/12/05)
Hepatitis C virus inhibitors having the general formula are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
HEPATITIS C VIRUS INHIBITORS
-
Page 337-338, (2008/06/13)
Hepatitis C virus inhibitors are disclosed having the general formula:(I) wherein R1, R2, R3, R', B, Y and X are described in the description. Compositions comprising the compounds and methods for using the compounds toinhibit HCV are also disclosed.
