4102-54-9

Basic information

• Product Name: 2,4-DIMETHYL-6-IODOANILINE
• Synonyms: 2-IODO-4,6-DIMETHYLANILINE;2,4-DIMETHYL-6-IODOANILINE;6-IODO-2,4-DIMETHYLBENZENAMINE
• CAS NO: 4102-54-9
• Molecular Formula: C₈H₁₀IN
• Molecular Weight: 247.08
• Mol File: 4102-54-9.mol
• Article Data: 18

Chemical Properties

• Melting Point: 64-65℃
• Appearance: /
• Storage Temp.: 2-8°C
• Water Solubility: Insoluble in water.
• Sensitive: Light Sensitive
• CAS DataBase Reference: 2,4-DIMETHYL-6-IODOANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-DIMETHYL-6-IODOANILINE(4102-54-9)
• EPA Substance Registry System: 2,4-DIMETHYL-6-IODOANILINE(4102-54-9)

Safety Data

• HazardClass: 6.1
• Hazardous Substances Data: 4102-54-9(Hazardous Substances Data)

Usage

Uses

It is employed in the synthesis of benzothiazoles through copper-catalyzed one-pot three-component reactions with use of sodium hydrosulfide as a sulfur surrogate.

Upstream product

• 95-68-1 2,4-Xylidine 
• 7647-01-0 hydrogenchloride 
• 7790-99-0 Iodine monochloride 
• 7664-93-9 sulfuric acid 

Downstream Products

• 859783-58-7 2-iodo-N-4,6-trimethylaniline 
• 132588-51-3 N-(1',1'-dimethylprop-2'-ynyl)-2-iodo-4,6-dimethylaniline 
• 180624-12-8 4,6-dimethyl-2-[2-(trimethylsilyl)ethynyl]aniline 
• 259865-72-0 N-allyl-2-iodo-4,6-dimethylaniline 
• 253304-53-9 N-(2-iodo-4,6-dimethylphenyl)-trans-crotonamide 
• 720714-03-4 N-(2-iodo-4,6-dimethylphenyl)-2-phenylacetamide 
• 1258410-35-3 2-iodo-N,N,4,6-tetramethylbenzenamine 
• 1242292-52-9 2-(4-methoxyphenyl)-4,6-dimethylbenzothiazole 
• 1374581-46-0 4-(4,6-dimethylbenzothiazol-2-yl)-N,N-dimethylaniline 
• 1374687-52-1 C₂₄H₂₄N₂O₄S 
• 1403488-37-8 4-(2-amino-3,5-dimethylphenyl)-2-methylbut-3-yn-2-ol 
• 1403488-46-9 4-(3,5-dimethyl-2-((2,2,6,8-tetramethyl-2,3-dihydroquinolin-4(1H)-ylidene)amino)phenyl)-2-methylbut-3-yn-2-ol 
• 1431884-80-8 C₁₂H₁₇N 
• 1431884-76-2 C₁₇H₂₁NO₂ 

Relevant articles and documents

Synthesis, structure, and heck cyclization of the syn- and anti-atropisomers of N-acyl-N-(4-methyl-3,6-dihydro-2H-pyran-3-yl)-2-iodo-4,6- dimethylaniline

The reaction of 2-iodo-2,4-dimethylaniline with 3,4-dibromo-4- methyltetrahydro-2H-pyran, followed by treatment with acetyl bromide or 4-nitrobenzoyl chloride, gave syn- and anti-atropisomers of N-(2-iodo-4,6- dimethylphenyl)-N-(4-methyl-3,6-dihydro-2H-py

A Diastereoselective Route to Benzoannelated Bridged Sultams

A practical diastereoselective method for the synthesis of benzoannelated tri- and tetracyclic bridged sultams has been developed. The synthetic route employs widely available, substituted -iodoanilines and is based on intramolecular Michael addition followed by cycloalkylation with dihaloalkanes, or vice versa. The target compounds were isolated in good yields and the diastereoselectivity of the reaction could be easily controlled by the order of Michael addition and cycloalkylation steps.

Method for preparing o-haloaromaticamine from C-H-based activated arylamines

The invention belongs to the technical field of organic chemistry and particularly relates to a method for preparing o-haloaromaticamine from C-H-based activated arylamines. The method comprises the following steps: taking anhydrous copper acetate as a reaction catalyst and hydrogen peroxide as an oxidizing agent, adding aniline compounds and potassium bromide or potassium iodide into water for reaction at room temperature for 2 h, extracting with ethyl acetate and concentrating under reduced pressure, so as to obtain a corresponding arylamine halogenated compound crude product; and performing column chromatographic isolation and purification to obtain a corresponding purified product. The method has the characteristics that the operation is simple, reaction conditions are mild, the reaction time is short, and the method is environment-friendly.