4104-35-2Relevant academic research and scientific papers
Metal-Free [3+2] Annulation of Ynamides with Anthranils to Construct 2-Aminoindoles
Zhang, Jingyi,Li, Ying,Zhang, Chaofeng,Wang, Xiao-Na,Chang, Junbiao
supporting information, p. 2029 - 2035 (2021/04/05)
A novel metal-free [3+2] annulation of ynamides with anthranils provides a facile, flexible, environmentally friendly, and atom-economical route to 2-aminoindoles. This synthetic process proceeds with efficiency, excellent regioselectivity, and wide functional group tolerance under mild conditions. Moreover, the obtained 2-aminoindole products represent a multifunctional platform for the construction of various 2-aminoindolyl frameworks.
Base-Mediated [3 + 4]-Cycloaddition of Anthranils with Azaoxyallyl Cations: A New Approach to Multisubstituted Benzodiazepines
Feng, Juan,Zhou, Meng,Lin, Xuanzi,Lu, An,Zhang, Xiaoyi,Zhao, Ming
supporting information, p. 6245 - 6248 (2019/09/06)
A new [3 + 4] cycloaddition of azaoxyallyl cations and anthranils has been achieved for rapid access to multisubstituted benzodiazepine derivatives. A variety of anthranils and α-halo hydroxamates were both effective substrates with simple operations unde
Rh(II)-Catalyzed Transannulation of N-Sulfonyl-1,2,3-Triazoles with 2,1-Benzisoxazoles or 1,2-Benzisoxazoles
Lei, Xiaoqiang,Gao, Mohan,Tang, Yefeng
supporting information, p. 4990 - 4993 (2016/10/14)
A Rh(II)-catalyzed transannulation of N-sulfonyl-1,2,3-triazoles with 2,1-benzisoxazoles has been developed, which affords an efficient method for the synthesis of quinazoline derivatives. The transformation represents an unprecedented example which utilizes N-sulfonyl-1,2,3-triazole as an aza-[2C]-component in cycloadditions. Meanwhile, a Rh(II)-catalyzed formal [3 + 2] cycloaddition of N-sulfonyl-1,2,3-triazoles with 1,2-benzisoxazoles is also presented, which enables the rapid synthesis of functionalized imidazole derivatives.
