4107-02-2Relevant academic research and scientific papers
Method for treating conditions related to the glutamate receptor using carboxylic acid amide derivatives
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, (2008/06/13)
The present invention is concerned with the use of carbonylamino derivatives of the formula wherein R signifies lower alkyl, lower alkenyl, lower alkinyl, cycloalkyl, lower alkoxy or CF3; R1signifies hydrogen or lower alkyl; R2and R3signify, independently from each other, hydrogen, halogen or nitro; Y signifies CH or N; n is 0-6; m is 0-2; as well as with their pharmaceutically acceptable salts for the treatment of diseases, which relate to metabotropic glutamate receptor antagonists and/or agonists.
Rearrangements of trihalomethyl ketones
Braverman, Samuel,Cherkinsky, Marina,Kumar, E. V. K. Suresh,Gottlieb, Hugo E.
, p. 4521 - 4529 (2007/10/03)
Trihalomethyl ketones have been prepared and their reactivity under basic conditions was investigated in terms of competition between 1,2- vs. 1,3-elimination and nucleophilic substitution. Favorskii rearrangement was the preferred process, but in those c
