41070-23-9Relevant academic research and scientific papers
Iridium(III)-Catalyzed C-H Functionalization of Triarylphosphine Oxides with Diazo Dicarbonyl Compounds: Synthesis of α-Aryl 1,3-Dicarbonyl Derivatives
Lou, Qin-Xin,Li, Jing-Yu,Yang, Shang-Dong
supporting information, (2021/04/15)
A novel (pentamethylcyclopenta-1,3-dienyl)iridium(III)-catalyzed direct C-H functionalization of triarylphosphine oxides with diazo dicarbonyl compounds through carbene insertion has been developed. This strategy provides a simple and efficient route to t
Method for synthesizing 1, 3-dicarbonyl compound based on terminal alkyne and acyl halide by one-pot process
-
Paragraph 0069-0074; 0132-0134, (2020/07/21)
The invention belongs to the technical field of catalytic synthesis, and discloses a method for synthesizing a 1, 3-dicarbonyl compound by a one-pot process, and the method comprises the following steps: by using simple palladium and copper salts as catalysts, reacting terminal alkyne with acyl halide at 0-80 DEG C for 0.5-12 hours under the action of trifluoromethanesulfonic acid to obtain the 1,3-dicarbonyl compound, wherein the molar ratio of the terminal alkyne to the acyl halide to the palladium salt to the copper salt to the trifluoromethanesulfonic acid is 1 to (1 to 2) to (0.00001 to0.10) to (0.00001 to 0.10) to (0.00004 to 0.40); the catalysts used in the method are common the commercialized palladium salt and copper salt, reagents used in the reaction are commercialized reagents, in addition, the raw materials are cheap and easy to obtain, functional group tolerance is good, reaction conditions are mild, operation is easy and convenient, and atom economy is high.
Palladium-catalyzed carbonylative α-arylation for accessing 1,3-diketones
Gogsig, Thomas M.,Taaning, Rolf H.,Lindhardt, Anders T.,Skrydstrup, Troels
supporting information; experimental part, p. 798 - 801 (2012/03/09)
With a hint of CO: The first Pd-catalyzed carbonylative α-arylations of simple ketones with carbon monoxide is presented for the direct synthesis of 1,3-diketones (see scheme). The method uses only stoichiometric amounts of CO, and hence allows for the si
CONDENSATION OF NITRILES WITH METHYL KETONES AS A METHOD FOR THE SYNTHESIS OF β-AMINOVINYL KETONES
Sosnovskikh, V. Ya.,Ovsyannikov, I. S.
, p. 1801 - 1805 (2007/10/02)
The condensation of nitriles containing aromatic substituents and of trichloroacetonitrile with methyl ketones in the presence of (phenylethylamino)magnesium bromide leads to β-aminovinyl ketones.Acid hydrolysis of the β-aminovinyl ketones gave high yields of the corresponding β-diketones.
