41114-00-5Relevant academic research and scientific papers
Iron-catalyzed AlkylAlkyl negishi coupling of organoaluminum reagents
Agata, Ryosuke,Kawamura, Shintaro,Isozaki, Katsuhiro,Nakamura, Masaharu
supporting information, p. 238 - 241 (2019/03/13)
The first iron-catalyzed cross-coupling reaction of alkyl halides with alkylaluminum reagents (alkylalkyl Negishi coupling) is developed using an iron/bisphosphine catalyst system. The reaction shows high functional group tolerance: various primary alkyl halides possessing a non-protected indole, carboxyl, or hydroxy group are coupled with primary alkylaluminum reagents in good yields. Potassium fluoride plays a key role to promote the reaction by generating an aluminate species, which facilitates the transmetalation between the organoaluminum and the iron catalyst.
Indium(III) acetate-catalyzed intermolecular radical addition of organic iodides to electron-deficient alkenes
Miura, Katsukiyo,Tomita, Mitsuru,Ichikawa, Junji,Hosomi, Akira
, p. 133 - 136 (2008/09/16)
In the presence of phenylsilane and a catalytic amount of indium(III) acetate, organic iodides added to electron-deficient alkenes in ethanol at room temperature. Both simple and functionalized organic iodides were applicable to this reaction. A plausible reaction mechanism involves the formation of indium hydride species by hydride transfer from silicon to indium and an indium hydride-mediated radical chain process.
Selective Mono- and Bis(alkoxycarbonylation)s of Olefins Catalyzed by Palladium in the Presence of Cu(I) or Cu(II) Chloride under Remarkably Mild Conditions. Application to the Synthesis of γ-Butyrolactone Derivatives
Toda, Shiho,Miyamoto, Masanori,Kinoshita, Hideki,Inomata, Katsuhiko
, p. 3600 - 3606 (2007/10/02)
Palladium-catalyzed mono- and bis(alkoxycarbonylation)s of the olefins were controlled by the use of copper(II) and copper(I) chloride, respectively, in alcohol under normal pressure of carbon monoxide and oxygen at room temperature without any other additives. 3-Buten-1-ols gave the corresponding γ-butyrolactones and 2-oxotetrahydrofuran-3-acetic acid esters, respectively, in high yields.
Selective Mono- and Dicarbonylation of Terminal Olefins Catalyzed by Pd-C in the Presence of Cu(II) or Cu(I) Chloride under Mild Conditions
Inomata, Katsuhiko,Toda, Shiho,Kinoshita, Hideki
, p. 1567 - 1570 (2007/10/02)
Pd-C can catalyze the carbonylation of terminal olefins with normal pressure of carbon monoxide at room temperature.The corresponding mono- and diesters (succinates) were selectively formed in excellent yields using Cu(II) and Cu(I) chloride, respectively, in alcohol.
