41118-21-2

Usage

Uses

Used in Perfumery and Cosmetics Industry:
Coumarin is used as a fragrance ingredient in perfumes and cosmetic products due to its sweet, pleasant odor. Its natural occurrence and appealing scent make it a popular choice for enhancing the olfactory experience of these products.
Used in Food and Beverage Industry:
As a flavoring agent, coumarin is incorporated into food and beverages to impart a unique taste and aroma. Its natural presence in certain plants and its ability to enhance flavors make it a valuable addition to the culinary world.
Used in Pharmaceutical Applications:
Coumarin is studied for its potential medicinal properties, such as its anticoagulant and anti-inflammatory effects. It is used as a starting material for the synthesis of various pharmaceutical compounds that can be employed in the treatment of different medical conditions.
Used in Research and Development:
Due to its unique chemical structure and potential health benefits, coumarin is utilized in research and development for the discovery of new drugs and therapeutic agents. Its properties are being investigated to understand its mechanisms of action and to develop novel applications in medicine.

Upstream product

• 67-56-1 methanol 
• 201230-82-2 carbon monoxide 
• 151884-08-1 4-oxochroman-7-yl trifluoromethanesulfonate 
• 90921-09-8 acide chromannone-4 carboxylique-7 
• 108-46-3 recorcinol 
• 151884-07-0 2',4'-dihydroxy-3-chloropropiophenone 
• 42327-52-6 7-methoxy-chroman-4-one 
• 76240-27-2 7-hydroxy-2,3-dihydro-4H-chromen-4-one 

Downstream Products

• 911376-43-7 methyl 4-[(trans-4-tert-butylcyclohexyl)amino]chromane-7-carboxylate 
• 929010-44-6 4-[1-(4-tert-butyl-cyclohexyl)-3-(4-trifluoromethoxy-phenyl)-ureido]-chroman-7-carboxylic acid methyl ester 
• 911376-45-9 methyl 4-[(4-cyclohexylphenyl)amino]chromane-7-carboxylate 
• 1023650-07-8 methyl 3-(4-fluorobenzylidene)-4-oxochroman-7-carboxylate 

Relevant academic research and scientific papers

HETEROCYCLIC COMPOUNDS WITH AN ROR(GAMMA)T MODULATING ACTIVITY

The present invention relates to a compound that may have an ROR(gamma)t modulating activity and can thus be useful in the treatment of cancer.

Anti-tumor drug benzodihydropyran (thiopyran) amide compound and its pharmaceutically acceptable salts and preparation method and application

The invention relates to new compounds benzodihydropyran(thiapyran)amide compounds represented by general formula I, or pharmaceutically acceptable salts of the compounds. The compounds or the pharmaceutically acceptable salts thereof are used as an antit

Design and synthesis of conformationally constrained tri-substituted ureas as potent antagonists of the human glucagon receptor

A series of conformationally constrained tri-substituted ureas were synthesized, and their potential as glucagon receptor antagonists was evaluated. This effort resulted in the identification of compound 4a, which had a binding IC50 of 4.0 nM a

A new class of bradykinin 1 receptor antagonists containing the piperidine acetic acid tetralin core

The bradykinin 1 (B1) receptor is upregulated during times of inflammation and is important for maintaining inflamed and chronic pain states. Blocking this receptor has been shown to reverse and/or ameliorate pain and inflammation in animal models. In this report, we describe a new class of B1 receptor antagonists that contain the piperidine acetic acid tetralin core. A structure-activity relationship for these analogs is described in this paper. The most potent compounds from this class have IC50s 20 nM in a B1 receptor functional assay. One of these compounds, 13g, shows modest oral bioavailability in rats.