41118-21-2Relevant articles and documents
HETEROCYCLIC COMPOUNDS WITH AN ROR(GAMMA)T MODULATING ACTIVITY
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Paragraph 0573, (2018/03/06)
The present invention relates to a compound that may have an ROR(gamma)t modulating activity and can thus be useful in the treatment of cancer.
Design and synthesis of conformationally constrained tri-substituted ureas as potent antagonists of the human glucagon receptor
Liang, Rui,Abrardo, Lauren,Brady, Edward J.,Candelore, Mari Rios,Ding, Victor,Saperstein, Richard,Tota, Laurie M.,Wright, Michael,Mock, Steve,Tamvakopolous, Constantin,Tong, Sharon,Zheng, Song,Zhang, Bei B.,Tata, James R.,Parmee, Emma R.
, p. 587 - 592 (2007/10/03)
A series of conformationally constrained tri-substituted ureas were synthesized, and their potential as glucagon receptor antagonists was evaluated. This effort resulted in the identification of compound 4a, which had a binding IC50 of 4.0 nM a
General preparation of 7-substituted 4-chromanones: Synthesis of a potent aldose reductase inhibitor
Koch,Biggers
, p. 1216 - 1218 (2007/10/02)
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