411221-64-2Relevant academic research and scientific papers
Site-recognition of one of the two alkoxy carbonyl groups present in the dienophile for Diels-Alder reaction
Kobayashi, Yuichi,Kiyotsuka, Yohei
, p. 9229 - 9232 (2001)
Recognition of one alkoxy carbonyl group from the two in a molecule by a Lewis acid was investigated using 1a-e in the Diels-Alder reaction with diene 6. Combination of 1a and BF3·OEt2 provided the highest efficiency to afford 7a, thus showing evidence for the site-selective coordination of BF3·OEt2 to the MOM-oxy carbonyl group in 1a. Furthermore, the generality and high reactivity of this combination were confirmed with dienes 11-14.
