411222-61-2Relevant academic research and scientific papers
A five-component synthesis of hexasubstituted benzene
Janvier, Pierre,Bienayme, Hugues,Zhu, Jieping
, p. 4291 - 4294 (2002)
Seven functional groups are involved in a highly ordered five-component domino process, which leads to a biologically relevant polyheterocycle. In this one-pot transformation, the formation of seven chemical bonds provides a hexasubstituted benzene core (
Ammonium chloride-promoted four-component synthesis of pyrrolo[3,4-b] pyridin-5-one
Janvier, Pierre,Sun, Xiaowen,Bienayme, Hugues,Zhu, Jieping
, p. 2560 - 2567 (2007/10/03)
A novel multicomponent synthesis of 5-aminooxazole starting from simple and readily available inputs is described. Thus, simply heating a methanol solution of an aldehyde 3, an amine 4, and an α-isocyanoacetamide 5 provided the 5-aminooxazole (1) in good
