411234-28-1Relevant articles and documents
Synthesis and biological activity of phosphonoacetate- and thiophosphonoacetate-modified 2′-O-methyl oligoribonucleotides
Threlfall, Richard N.,Torres, Adrian G.,Krivenko, Angelika,Gait, Michael J.,Caruthers, Marvin H.
experimental part, p. 746 - 754 (2012/02/05)
Chimeric 2′-O-methyl oligoribonucleotides (2′-OMe ORNs) containing internucleotide linkages which were modified with phosphonoacetate (PACE) or thiophosphonoacetate (thioPACE) were prepared by solid-phase synthesis. The modified 2′-OMe ORNs contained a ce