4118-63-2

Basic information

• Product Name: 3,5-anhydro-1,2-O-isopropylidene-α-D-xylofuranose
• Synonyms: 3,5-anhydro-1,2-O-isopropylidene-α-D-xylofuranose
• CAS NO: 4118-63-2
• Molecular Weight: 172.181
• Mol File: 4118-63-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3,5-anhydro-1,2-O-isopropylidene-α-D-xylofuranose(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-anhydro-1,2-O-isopropylidene-α-D-xylofuranose(4118-63-2)
• EPA Substance Registry System: 3,5-anhydro-1,2-O-isopropylidene-α-D-xylofuranose(4118-63-2)

Safety Data

• Hazardous Substances Data: 4118-63-2(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 6893-65-8 1,2-di-O-isopropylidene-5-O-tosyl-D-xylofuranose 

Downstream Products

• 23202-83-7 5-benzyl-1,2-O-isopropylidene-α-D-xylofuranose 
• 153974-94-8 (3aR,5R,6S,6aR)-5-((3aR,5R,6S,6aR)-5-Benzyloxymethyl-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yloxymethyl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-ol 
• 4152-79-8 1,2-O-isopropylidene-5-methyl-5-deoxy-α-D-xylofuranose 
• 253128-10-8 3-((2S,5S)-5-(2-((2S,4R,6R)-6-(((2S,3S,4R,5R)-5-((S)-2,3-bis((tert-butyldimethylsilyl)oxy)propyl)-4-methoxy-3-((phenylsulfonyl)methyl)tetrahydrofuran-2-yl)methyl)-4-methyl-5-methylenetetrahydro-2H-pyran-2-yl)ethyl)-4-methylenetetrahydrofuran-2-yl)propan-1-ol 
• 546141-37-1 (3aR,5R,6S,6aR)-5-allyl-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-6-ol 
• 1384524-73-5 2-(acetylamino)-9-[2-O-acetyl-3-azido-3,5-dideoxy-5-(triisopropylsilyl)ethynyl-β-D-ribofuranosyl]-6-(diphenylcarbamoyloxy)-9H-purine 
• 74996-04-6 5-deoxy-5-diphenylphosphino-1,2-O-isopropylidene-α-D-xylofuranose 
• 3396-71-2 3-deoxy-1,2-O-isopropylidene-α-D-ribofuranose 

Relevant articles and documents

Synthesis and biological evaluation of deoxy salacinols, the role of polar substituents in the side chain on the α-glucosidase inhibitory activity

Three analogs (5, 6, and 7) lacking polar substituents in the side chain of a naturally occurring α-glucosidase inhibitor, salacinol (1a), were synthesized by the coupling reaction of a thiosugar, 1,4-dideoxy-1,4-epithio-d- arabinitol (3), with cyclic sulfates (8, 9, and 10), and their α-glucosidase inhibitory activities were examined. All these simpler analogs (5, 6, and 7) showed less inhibitory activity compared to 1a, and proved the importance of cooperative role of the polar substituents for the α-glucosidase inhibitory activity. A practical synthetic route to 3 starting from d-xylose is also described.